Evaluation of Different Formulations and Routes for the Delivery of the Ionizing Radiation Mitigator GS-Nitroxide (JP4-039)

. Background/Aim: The mitochondrial targeted GS-nitroxide, JP4-039, is an effective total body irradiation (TBI) mitigator when delivered intravenously (IV) up to 72 h after exposure. Effective systemic and localized administration to oral cavity/oropharynx and esophagus has been demonstrated. The o...

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Bibliografiske detaljer
Udgivet i:In Vivo
Main Authors: EPPERLY, MICHAEL W., WIPF, PETER, FISHER, RENEE, FRANICOLA, DARCY, BEUMER, JAN, LI, SONG, BRAND, RHONDA M., FALO, LOUISD.Jr, ERDOS, GEZA, GREENBERGER, JOEL S.
Format: Artigo
Sprog:Inglês
Udgivet: International Institute of Anticancer Research 2018
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6199586/
https://ncbi.nlm.nih.gov/pubmed/30150422
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.21873/invivo.11341
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