Sustained JNK Activity Promotes Epithelial-Mesenchymal Transition, Invasion, and Survival of Breast Cancer Cells by Regulating ERK Activation

od Wang, Jinhua, Kuiatse, Isere, Lee, Adrian V., Pan, Jingxuan, Giuliano, Armando, Cui, Xiaojiang
Izdano 2010

Dynamic balance of multiple myeloma clonogenic side population cell percentages controlled by environmental conditions

od Wen, Jianguo, Tao, Wenjing, Kuiatse, Isere, Lin, Pei, Feng, Yongdong, Jones, Richard J., Orlowski, Robert Z., Zu, Youli
Izdano u Int J Cancer (2014)

The Novel Anticancer Agent JNJ-26854165 Induces Cell Death through Inhibition of Cholesterol Transport and Degradation of ABCA1

od Jones, Richard J., Gu, Dongmin, Bjorklund, Chad C., Kuiatse, Isere, Remaley, Alan T., Bashir, Tarig, Vreys, Veronique, Orlowski, Robert Z.
Izdano 2013

A moderate elevation of circulating levels of IGF-I does not alter ErbB2 induced mammary tumorigenesis

od Brown Powel H, Hilsenbeck Susan G, Liao Lan, Wang Yu-Fen, Kuiatse Isere, Dearth Robert K, Xu Jianming, Lee Adrian V
Izdano 2011-08-01

A moderate elevation of circulating levels of IGF-I does not alter ErbB2 induced mammary tumorigenesis

od Dearth, Robert K, Kuiatse, Isere, Wang, Yu-Fen, Liao, Lan, Hilsenbeck, Susan G, Brown, Powel H, Xu, Jianming, Lee, Adrian V
Izdano 2011

The Nuclear Factor (Erythroid-derived 2)-like 2 and Proteasome Maturation Protein Axis Mediate Bortezomib Resistance in Multiple Myeloma

od Li, Bingzong, Fu, Jinxiang, Chen, Ping, Ge, Xueping, Li, Yali, Kuiatse, Isere, Wang, Hua, Wang, Huihan, Zhang, Xingding, Orlowski, Robert Z.
Izdano u J Biol Chem (2015)

BMS-536924 Reverses IGF-IR-induced Transformation of Mammary Epithelial Cells and Causes Growth Inhibition and Polarization of MCF7 Cells

od Litzenburger, Beate C., Kim, Hyun-Jung, Kuiatse, Isere, Carboni, Joan M., Attar, Ricardo M., Gottardis, Marco M., Fairchild, Craig R., Lee, Adrian V.
Izdano 2009

Inhibition of the MDM2 E3 Ligase Induces Apoptosis and Autophagy in Wild-Type and Mutant p53 Models of Multiple Myeloma, and Acts Synergistically with ABT-737

od Gu, Dongmin, Wang, Shuhong, Kuiatse, Isere, Wang, Hua, He, Jin, Dai, Yun, Jones, Richard J., Bjorklund, Chad C., Yang, Jing, Grant, Steven, Orlowski, Robert Z.
Izdano 2014

Intravenous Immunoglobulin G Suppresses Heat Shock Protein (HSP)-70 Expression and Enhances the Activity of HSP90 and Proteasome Inhibitors

od Jones, Richard J., Singh, Ram K., Shirazi, Fazal, Wan, Jie, Wang, Hua, Wang, Xiaobin, Ha, Min Jin, Baljevic, Muhamed, Kuiatse, Isere, Davis, Richard E., Orlowski, Robert Z.
Izdano u Front Immunol (2020)

Activating KRAS, NRAS, and BRAF mutants enhance proteasome capacity and reduce endoplasmic reticulum stress in multiple myeloma

od Shirazi, Fazal, Jones, Richard J., Singh, Ram K., Zou, Jianxuan, Kuiatse, Isere, Berkova, Zuzana, Wang, Hua, Lee, Hans C., Hong, Samuel, Dick, Larry, Chattopadhyay, Nibedita, Orlowski, Robert Z.
Izdano u Proc Natl Acad Sci U S A (2020)

Estrogen and Insulin-like Growth Factor-I (IGF-I) Independently Down-regulate Critical Repressors of Breast Cancer Growth

od Casa, Angelo J., Potter, Adam, Malik, Simeen, Lazard, ZaWaunyka, Kuiatse, Isere, Kim, Hee-Tae, Tsimelzon, Anna, Creighton, Chad, Hilsenbeck, Susan G., Brown, Powel H., Oesterreich, Steffi, Lee, Adrian V.
Izdano 2011

Mammary Tumorigenesis and Metastasis Caused by Overexpression of Insulin Receptor Substrate 1 (IRS-1) or IRS-2

od Dearth, Robert K., Cui, Xiaojiang, Kim, Hyun-Jung, Kuiatse, Isere, Lawrence, Nicole A., Zhang, Xiaomei, Divisova, Jana, Britton, Ora L., Mohsin, Syed, Allred, D. Craig, Hadsell, Darryl L., Lee, Adrian V.
Izdano 2006

Evidence of a Role for CD44 and Cell Adhesion in Mediating Resistance to Lenalidomide in Multiple Myeloma: Therapeutic Implications

od Bjorklund, Chad C., Baladandayuthapani, Veerabhadran, Lin, Heather Y., Jones, Richard J., Kuiatse, Isere, Wang, Hua, Yang, Jing, Shah, Jatin J., Thomas, Sheeba K., Wang, Michael, Weber, Donna M., Orlowski, Robert Z.
Izdano 2013

RNA Polymerase I Inhibition with CX-5461 as a Novel Therapeutic Strategy to Target MYC in Multiple Myeloma

od Lee, Hans C., Wang, Hua, Baladandayuthapani, Veerabhadran, Lin, Heather, He, Jin, Jones, Richard J., Kuiatse, Isere, Gu, Dongmin, Wang, Zhiqiang, Ma, Wencai, Lim, John, O’Brien, Sean, Keats, Jonathan, Yang, Jing, Davis, Richard E., Orlowski, Robert Z.
Izdano u Br J Haematol (2017)

Targeting the Spleen Tyrosine Kinase with Fostamatinib as a Strategy Against Waldenström’s Macroglobulinemia

od Kuiatse, Isere, Baladandayuthapani, Veerabhadran, Lin, Heather Y., Thomas, Sheeba K., Bjorklund, Chad C., Weber, Donna M., Wang, Michael, Shah, Jatin J., Zhang, Xing-Ding, Jones, Richard J., Ansell, Stephen M., Yang, Guang, Treon, Steven P., Orlowski, Robert Z.
Izdano u Clin Cancer Res (2015)

Targeting Myddosome Signaling in Waldenström’s Macroglobulinemia with the Interleukin-1 Receptor-associated Kinase 1/4 Inhibitor R191

od Haiwen, Ni, Shirazi, Fazal, Baladandayuthapani, Veerabhadran, Lin, Heather, Kuiatse, Isere, Wang, Hua, Jones, Richard J., Berkova, Zuzana, Hitoshi, Yasumichi, Ansell, Stephen M., Treon, Steven P., Thomas, Sheeba K., Lee, Hans C., Wang, Zhiqiang, Davis, R. Eric, Orlowski, Robert Z.
Izdano u Clin Cancer Res (2018)

Ubiquitin-activating enzyme inhibition induces an unfolded protein response and overcomes drug resistance in myeloma

od Zhuang, Junling, Shirazi, Fazal, Singh, Ram Kumar, Kuiatse, Isere, Wang, Hua, Lee, Hans C., Berkova, Zuzana, Berger, Allison, Hyer, Marc, Chattopadhyay, Nibedita, Syed, Sakeena, Shi, Judy Qiuju, Yu, Jie, Shinde, Vaishali, Tirrell, Stephen, Jones, Richard Julian, Wang, Zhiqiang, Davis, R. Eric, Orlowski, Robert Z.
Izdano u Blood (2019)

Protein Targeting Chimeric Molecules Specific for Bromodomain and Extra-terminal Motif Family Proteins are Active Against Pre-Clinical Models of Multiple Myeloma

od Zhang, Xiaohui, Lee, Hans C., Shirazi, Fazal, Baladandayuthapani, Veerabhadran, Lin, Heather, Kuiatse, Isere, Wang, Hua, Jones, Richard J., Berkova, Zuzana, Singh, Ram Kumar, Lu, Jing, Qian, Yimin, Raina, Kanak, Coleman, Kevin G., Crews, Craig M., Li, Bingzong, Wang, Huihan, Hailemichael, Yared, Thomas, Sheeba K., Wang, Zhiqiang, Davis, R. Eric, Orlowski, Robert Z.
Izdano u Leukemia (2018)

HSP90 inhibition enhances cancer immunotherapy by upregulating interferon response genes

od Mbofung, Rina M., McKenzie, Jodi A., Malu, Shruti, Zhang, Min, Peng, Weiyi, Liu, Chengwen, Kuiatse, Isere, Tieu, Trang, Williams, Leila, Devi, Seram, Ashkin, Emily, Xu, Chunyu, Huang, Lu, Zhang, Minying, Talukder, Amjad H., Tripathi, Satyendra C., Khong, Hiep, Satani, Nikunj, Muller, Florian L., Roszik, Jason, Heffernan, Timothy, Allison, James P., Lizee, Gregory, Hanash, Sam M., Proia, David, Amaria, Rodabe, Davis, R. Eric, Hwu, Patrick
Izdano u Nat Commun (2017)

Tight Junction Protein 1 Modulates Proteasome Capacity and Proteasome Inhibitor Sensitivity in Multiple Myeloma via EGFR/JAK1/STAT3 Signaling

od Zhang, Xing-Ding, Baladandayuthapani, Veerabhadran, Lin, Heather, Mulligan, George, Li, Bin, Esseltine, Dixie-Lee W., Qi, Lin, Xu, Jianliang, Hunziker, Walter, Barlogie, Bart, Usmani, Saad Z., Zhang, Qing, Crowley, John, Hoering, Antje, Shah, Jatin J., Weber, Donna M., Manasanch, Elisabet E., Thomas, Sheeba K., Li, Bing-Zong, Wang, Hui-Han, Zhang, Jiexin, Kuiatse, Isere, Tang, Jin-Le, Wang, Hua, Jin, He, Yang, Jing, Milan, Enrico, Cenci, Simone, Ma, Wen-Cai, Wang, Zhi-Qiang, Davis, Richard Eric, Yang, Lin, Orlowski, Robert Z.
Izdano u Cancer Cell (2016)