The Nuclear Factor (Erythroid-derived 2)-like 2 and Proteasome Maturation Protein Axis Mediate Bortezomib Resistance in Multiple Myeloma

Resistance to the proteasome inhibitor bortezomib is an emerging clinical problem whose mechanisms have not been fully elucidated. We considered the possibility that this could be associated with enhanced proteasome activity in part through the action of the proteasome maturation protein (POMP). Bor...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Li, Bingzong, Fu, Jinxiang, Chen, Ping, Ge, Xueping, Li, Yali, Kuiatse, Isere, Wang, Hua, Wang, Huihan, Zhang, Xingding, Orlowski, Robert Z.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2015
Assuntos:
Molecular Bases of Disease
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4705994/
https://ncbi.nlm.nih.gov/pubmed/26483548
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.664953
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