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Proteasome Inhibitors in the Treatment of Multiple Myeloma
Targeting intracellular protein turnover by inhibiting the ubiquitin-proteasome pathway as a strategy for cancer therapy is a new addition to our chemotherapeutic armamentarium, and has seen its greatest successes against multiple myeloma. The first-in-class proteasome inhibitor bortezomib was initi...
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| Publicado no: | Leukemia |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4737506/ https://ncbi.nlm.nih.gov/pubmed/19741722 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/leu.2009.173 |
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