Temperature-Sensitive Lethal Mutations on Yeast Chromosome I Appear to Define Only a Small Number of Genes

Por Kaback, David B., Oeller, Paul W., Steensma, H. Yde, Hirschman, Janet, Ruezinsky, Diane, Coleman, Kevin G., Pringle, John R.
Publicado em 1984

Dwarfism, impaired skin development, skeletal muscle atrophy, delayed bone development, and impeded adipogenesis in mice lacking Akt1 and Akt2

Por Peng, Xiao-ding, Xu, Pei-Zhang, Chen, Mei-Ling, Hahn-Windgassen, Annett, Skeen, Jennifer, Jacobs, Joel, Sundararajan, Deepa, Chen, William S., Crawford, Susan E., Coleman, Kevin G., Hay, Nissim
Publicado em 2003

Severe diabetes, age-dependent loss of adipose tissue, and mild growth deficiency in mice lacking Akt2/PKBβ

Por Garofalo, Robert S., Orena, Stephen J., Rafidi, Kristina, Torchia, Anthony J., Stock, Jeffrey L., Hildebrandt, Audrey L., Coskran, Timothy, Black, Shawn C., Brees, Dominique J., Wicks, Joan R., McNeish, John D., Coleman, Kevin G.
Publicado em 2003

PROTAC-induced BET protein degradation as a therapy for castration-resistant prostate cancer

Por Raina, Kanak, Lu, Jing, Qian, Yimin, Altieri, Martha, Gordon, Deborah, Rossi, Ann Marie K., Wang, Jing, Chen, Xin, Dong, Hanqing, Siu, Kam, Winkler, James D., Crew, Andrew P., Crews, Craig M., Coleman, Kevin G.
Publicado no Proc Natl Acad Sci U S A (2016)

Novel BET protein Proteolysis Targeting Chimera (BET-PROTAC) exerts superior lethal activity than Bromodomain Inhibitor (BETi) against post-myeloproliferative Neoplasm (MPN) Second...

Por Saenz, Dyana T., Fiskus, Warren, Qian, Yimin, Manshouri, Taghi, Rajapakshe, Kimal, Raina, Kanak, Coleman, Kevin G., Crew, Andrew P., Shen, Angela, Mill, Christopher P., Sun, Baohua, Qiu, Peng, Kadia, Tapan M., Pemmaraju, Naveen, DiNardo, Courtney, Kim, Mi-Sun, Nowak, Agnieszka J., Coarfa, Cristian, Crews, Craig M., Verstovsek, Srdan, Bhalla, Kapil N.
Publicado no Leukemia (2017)

Biochemical and pharmacological characterization of human c-Met neutralizing monoclonal antibody CE-355621

Por Michaud, Neil R., Jani, Jitesh P., Hillerman, Stephen, Tsaparikos, Konstantinos E., Barbacci-Tobin, Elsa G., Knauth, Elisabeth, Putz Jr., Henry, Campbell, Mary, Karam, George A., Chrunyk, Boris, Gebhard, David F., Green, Larry L., Xu, Jinghai J., Dunn, Margaret C., Coskran, Tim M., Lapointe, Jean-Martin, Cohen, Bruce D., Coleman, Kevin G., Bedian, Vahe, Vincent, Patrick, Kajiji, Shama, Steyn, Stefan J., Borzillo, Gary V., Los, Gerrit
Publicado em 2012