Biochemical and pharmacological characterization of human c-Met neutralizing monoclonal antibody CE-355621

The c-Met proto-oncogene is a multifunctional receptor tyrosine kinase that is stimulated by its ligand, hepatocyte growth factor (HGF), to induce cell growth, motility and morphogenesis. Dysregulation of c-Met function, through mutational activation or overexpression, has been observed in many type...

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Detaylı Bibliyografya
Asıl Yazarlar: Michaud, Neil R., Jani, Jitesh P., Hillerman, Stephen, Tsaparikos, Konstantinos E., Barbacci-Tobin, Elsa G., Knauth, Elisabeth, Putz Jr., Henry, Campbell, Mary, Karam, George A., Chrunyk, Boris, Gebhard, David F., Green, Larry L., Xu, Jinghai J., Dunn, Margaret C., Coskran, Tim M., Lapointe, Jean-Martin, Cohen, Bruce D., Coleman, Kevin G., Bedian, Vahe, Vincent, Patrick, Kajiji, Shama, Steyn, Stefan J., Borzillo, Gary V., Los, Gerrit
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Landes Bioscience 2012
Konular:
Report
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3502238/
https://ncbi.nlm.nih.gov/pubmed/23007574
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/mabs.22160
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