Evidence of a Role for CD44 and Cell Adhesion in Mediating Resistance to Lenalidomide in Multiple Myeloma: Therapeutic Implications

Resistance of myeloma to lenalidomide is an emerging clinical problem, and though it has been associated in part with activation of Wnt/β-catenin signaling, the mediators of this phenotype remained undefined. Lenalidomide-resistant models were found to overexpress the hyaluronan (HA)-binding protein...

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Detalhes bibliográficos
Main Authors: Bjorklund, Chad C., Baladandayuthapani, Veerabhadran, Lin, Heather Y., Jones, Richard J., Kuiatse, Isere, Wang, Hua, Yang, Jing, Shah, Jatin J., Thomas, Sheeba K., Wang, Michael, Weber, Donna M., Orlowski, Robert Z.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3874423/
https://ncbi.nlm.nih.gov/pubmed/23760401
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/leu.2013.174
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