Proteasome Inhibition Drives HDAC6-Dependent Recruitment of Tau to Aggresomes

Yazar: Guthrie, Chris R., Kraemer, Brian C.
Baskı/Yayın Bilgisi 2011

SUT-2 potentiates tau-induced neurotoxicity in Caenorhabditis elegans

Yazar: Guthrie, Chris R., Schellenberg, Gerard D., Kraemer, Brian C.
Baskı/Yayın Bilgisi 2009

Phosphorylation Promotes Neurotoxicity in a Caenorhabditis elegans Model of TDP-43 Proteinopathy

Yazar: Liachko, Nicole F., Guthrie, Chris R., Kraemer, Brian C.
Baskı/Yayın Bilgisi 2010

The role of MSUT-2 in tau neurotoxicity: a target for neuroprotection in tauopathy?

Yazar: Wheeler, Jeanna M., Guthrie, Chris R., Kraemer, Brian C.
Baskı/Yayın Bilgisi 2010

Potential neuroprotective strategies against tauopathy

Yazar: Wheeler, Jeanna M., Guthrie, Chris R., Kraemer, Brian C.
Yayımlandı Biochem Soc Trans (2012)

MSUT2 is a determinant of susceptibility to tau neurotoxicity

Yazar: Guthrie, Chris R., Greenup, Lynne, Leverenz, James B., Kraemer, Brian C.
Baskı/Yayın Bilgisi 2011

Genetic strategies to study TDP-43 in rodents and to develop preclinical therapeutics for amyotrophic lateral sclerosis

Yazar: Wang, David B., Gitcho, Michael A., Kraemer, Brian C., Klein, Ronald L.
Baskı/Yayın Bilgisi 2011

Tau tubulin kinases in proteinopathy

Yazar: Taylor, Laura M., McMillan, Pamela J., Kraemer, Brian C., Liachko, Nicole F.
Yayımlandı FEBS J (2019)

Synergistic toxicity between tau and amyloid drives neuronal dysfunction and neurodegeneration in transgenic C. elegans

Yazar: Benbow, Sarah J, Strovas, Timothy J, Darvas, Martin, Saxton, Aleen, Kraemer, Brian C
Yayımlandı Hum Mol Genet (2020)

DOPA decarboxylase modulates tau toxicity

Yazar: Kow, Rebecca L., Sikkema, Carl, Wheeler, Jeanna M., Wilkinson, Charles W., Kraemer, Brian C.
Yayımlandı Biol Psychiatry (2017)

Constitutive XBP-1s-mediated activation of the endoplasmic reticulum unfolded protein response protects against pathological tau

Yazar: Waldherr, Sarah M., Strovas, Timothy J., Vadset, Taylor A., Liachko, Nicole F., Kraemer, Brian C.
Yayımlandı Nat Commun (2019)

A drug repurposing screen identifies hepatitis C antivirals as inhibitors of the SARS-CoV2 main protease

Yazar: Baker, Jeremy D., Uhrich, Rikki L., Kraemer, Gerald C., Love, Jason E., Kraemer, Brian C.
Yayımlandı PLoS One (2021)

Truncation of tau at E391 Promotes Early Pathological Changes in Transgenic Mice

Yazar: McMillan, Pamela J., Kraemer, Brian C., Robinson, Linda, Leverenz, James B., Raskind, Murray, Schellenberg, Gerard
Baskı/Yayın Bilgisi 2011

Dopamine D2 Receptor antagonism suppresses tau aggregation and neurotoxicity

Yazar: McCormick, Allyson V., Wheeler, Jeanna M., Guthrie, Chris R., Liachko, Nicole F., Kraemer, Brian C.
Baskı/Yayın Bilgisi 2012

Neurodegeneration and defective neurotransmission in a Caenorhabditis elegans model of tauopathy

Yazar: Kraemer, Brian C., Zhang, Bin, Leverenz, James B., Thomas, James H., Trojanowski, John Q., Schellenberg, Gerard D.
Baskı/Yayın Bilgisi 2003

CDC7 inhibition blocks pathological TDP-43 phosphorylation and neurodegeneration

Yazar: Liachko, Nicole F., McMillan, Pamela J., Guthrie, Chris R., Bird, Thomas D., Leverenz, James B., Kraemer, Brian C.
Baskı/Yayın Bilgisi 2013

Loss of murine TDP-43 disrupts motor function and plays an essential role in embryogenesis

Yazar: Kraemer, Brian C., Schuck, Theresa, Wheeler, Jeanna M., Robinson, Linda C., Trojanowski, John Q., Lee, Virginia M. Y., Schellenberg, Gerard D.
Baskı/Yayın Bilgisi 2010

Erratum to: Ethosuximide ameliorates neurodegenerative disease phenotypes by modulating DAF-16/FOXO target gene expression

Yazar: Chen, Xi, McCue, Hannah V., Wong, Shi Quan, Kashyap, Sudhanva S., Kraemer, Brian C., Barclay, Jeff W., Burgoyne, Robert D., Morgan, Alan
Yayımlandı Mol Neurodegener (2015)

Genome wide analysis reveals heparan sulfate epimerase modulates TDP-43 proteinopathy

Yazar: Liachko, Nicole F., Saxton, Aleen D., McMillan, Pamela J., Strovas, Timothy J., Keene, C. Dirk, Bird, Thomas D., Kraemer, Brian C.
Yayımlandı PLoS Genet (2019)

Ethosuximide ameliorates neurodegenerative disease phenotypes by modulating DAF-16/FOXO target gene expression

Yazar: Chen, Xi, McCueF, Hannah V., Wong, Shi Quan, Kashyap, Sudhanva S., Kraemer, Brian C., Barclay, Jeff W., Burgoyne, Robert D., Morgan, Alan
Yayımlandı Mol Neurodegener (2015)