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MSUT2 is a determinant of susceptibility to tau neurotoxicity

Lesions containing abnormal aggregated tau protein are one of the diagnostic hallmarks of Alzheimer's disease (AD) and related tauopathy disorders. How aggregated tau leads to dementia remains enigmatic, although neuronal dysfunction and loss clearly contribute. We previously identified sut-2 a...

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Hlavní autoři: Guthrie, Chris R., Greenup, Lynne, Leverenz, James B., Kraemer, Brian C.
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3080609/
https://ncbi.nlm.nih.gov/pubmed/21355046
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddr079
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