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Dopamine D2 Receptor antagonism suppresses tau aggregation and neurotoxicity
BACKGROUND: Tauopathies, including Alzheimer’s disease (AD) and frontotemporal dementia, are diseases characterized by the formation of pathological tau protein aggregates in the brain and progressive neurodegeneration. Presently no effective disease modifying treatments exist for tauopathies. METHO...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3570611/ https://ncbi.nlm.nih.gov/pubmed/23140663 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biopsych.2012.08.027 |
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