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Dopamine D2 Receptor antagonism suppresses tau aggregation and neurotoxicity

BACKGROUND: Tauopathies, including Alzheimer’s disease (AD) and frontotemporal dementia, are diseases characterized by the formation of pathological tau protein aggregates in the brain and progressive neurodegeneration. Presently no effective disease modifying treatments exist for tauopathies. METHO...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: McCormick, Allyson V., Wheeler, Jeanna M., Guthrie, Chris R., Liachko, Nicole F., Kraemer, Brian C.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2012
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3570611/
https://ncbi.nlm.nih.gov/pubmed/23140663
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biopsych.2012.08.027
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