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Suppressing Tau Aggregation and Toxicity by an Anti-Aggregant Tau Fragment
Tau aggregation is a hallmark of a group of neurodegenerative diseases termed Tauopathies. Reduction of aggregation-prone Tau has emerged as a promising therapeutic approach. Here, we show that an anti-aggregant Tau fragment (F3(ΔKPP), residues 258–360) harboring the ΔK280 mutation and two proline s...
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| Publicado en: | Mol Neurobiol |
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| Autores principales: | , , , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Springer US
2018
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6476873/ https://ncbi.nlm.nih.gov/pubmed/30196394 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12035-018-1326-z |
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