The release and trans-synaptic transmission of Tau via exosomes

BACKGROUND: Tau pathology in AD spreads in a hierarchical pattern, whereby it first appears in the entorhinal cortex, then spreads to the hippocampus and later to the surrounding areas. Based on this sequential appearance, AD can be classified into six stages (“Braak stages”). The mechanisms and age...

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Detalhes bibliográficos
Publicado no:Mol Neurodegener
Main Authors: Wang, Yipeng, Balaji, Varun, Kaniyappan, Senthilvelrajan, Krüger, Lars, Irsen, Stephan, Tepper, Katharina, Chandupatla, RamReddy, Maetzler, Walter, Schneider, Anja, Mandelkow, Eckhard, Mandelkow, Eva-Maria
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5237256/
https://ncbi.nlm.nih.gov/pubmed/28086931
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13024-016-0143-y
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