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FRET-based Tau seeding assay does not represent prion-like templated assembly of Tau filaments
Tau aggregation into amyloid fibers based on the cross-beta structure is a hallmark of several Tauopathies, including Alzheimer Disease (AD). Trans-cellular propagation of Tau with pathological conformation has been suggested as a key disease mechanism. This is thought to cause the spreading of Tau...
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| 出版年: | Mol Neurodegener |
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| 主要な著者: | , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
BioMed Central
2020
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7364478/ https://ncbi.nlm.nih.gov/pubmed/32677995 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13024-020-00389-1 |
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