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SUT-2 potentiates tau-induced neurotoxicity in Caenorhabditis elegans
Expression of human tau in Caenorhabditis elegans neurons causes accumulation of aggregated tau leading to neurodegeneration and uncoordinated movement. We used this model of human tauopathy disorders to screen for genes required for tau neurotoxicity. Recessive loss-of-function mutations in the sut...
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| Asıl Yazarlar: | , , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
Oxford University Press
2009
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2722225/ https://ncbi.nlm.nih.gov/pubmed/19273536 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddp099 |
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