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The role of MSUT-2 in tau neurotoxicity: a target for neuroprotection in tauopathy?

We previously developed a transgenic Caenorhabditis elegans model of human tauopathy disorders by expressing human tau in nematode worm neurons to explore genetic pathways contributing to tau-induced neurodegeneration. This animal model recapitulates several hallmarks of human tauopathies, including...

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Autori principali: Wheeler, Jeanna M., Guthrie, Chris R., Kraemer, Brian C.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3103713/
https://ncbi.nlm.nih.gov/pubmed/20658987
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BST0380973
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