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Phosphorylation Promotes Neurotoxicity in a Caenorhabditis elegans Model of TDP-43 Proteinopathy

Neurodegenerative disorders characterized by neuronal and glial lesions containing aggregated pathological TDP-43 protein in the cytoplasm, nucleus, or neurites are collectively referred to as TDP-43 proteinopathies. Lesions containing aggregated TDP-43 protein are a hallmark of amyotrophic lateral...

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Библиографические подробности
Главные авторы: Liachko, Nicole F., Guthrie, Chris R., Kraemer, Brian C.
Формат: Artigo
Язык:Inglês
Опубликовано: Society for Neuroscience 2010
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3075589/
https://ncbi.nlm.nih.gov/pubmed/21123567
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2911-10.2010
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