Ethosuximide ameliorates neurodegenerative disease phenotypes by modulating DAF-16/FOXO target gene expression

BACKGROUND: Many neurodegenerative diseases are associated with protein misfolding/aggregation. Treatments mitigating the effects of such common pathological processes, rather than disease-specific symptoms, therefore have general therapeutic potential. RESULTS: Here we report that the anti-epilepti...

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Udgivet i:Mol Neurodegener
Main Authors: Chen, Xi, McCueF, Hannah V., Wong, Shi Quan, Kashyap, Sudhanva S., Kraemer, Brian C., Barclay, Jeff W., Burgoyne, Robert D., Morgan, Alan
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2015
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4587861/
https://ncbi.nlm.nih.gov/pubmed/26419537
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13024-015-0046-3
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