Adipose-derived Stromal Cells: The Good Side of Fat?

Por Kotlarz, Daniel, Biswas, Amlan
Publicado no Cell Mol Gastroenterol Hepatol (2018)

Dysregulation of Cell Death in Human Chronic Inflammation

Por Li, Yue, Klein, Christoph, Kotlarz, Daniel
Publicado no Cold Spring Harb Perspect Biol (2020)

IL-12Rβ1 deficiency corresponding to concurrency of two diseases, mendelian susceptibility to mycobacterial disease and Crohn's disease

Por Khoshnevisan, Razieh, Nekooei-marnany, Nioosha, Klein, Christoph, Kotlarz, Daniel, Behnam, Mahdieh, Ostadi, Vajihe, Yaran, Majid, Rezaei, Abbas, Sherkat, Roya
Publicado no J Clin Tuberc Other Mycobact Dis (2019)

Differential diagnosis in ulcerative colitis in an adolescent: Chronic granulomatous disease needs extra attention

Por Kotlarz, Daniel, Egritas Gurkan, Odul, Haskologlu, Zehra Sule, Ekinci, Ozgur, Aksu Unlusoy, Aysel, Gürcan Kaya, Neslihan, Puchalka, Jacek, Klein, Cristoph, Dalgic, Buket
Publicado no World J Gastrointest Pathophysiol (2017)

LAMTOR2 (p14) Controls B Cell Differentiation by Orchestrating Endosomal BCR Trafficking

Por Łyszkiewicz, Marcin, Kotlarz, Daniel, Ziȩtara, Natalia, Brandes, Gudrun, Diestelhorst, Jana, Glage, Silke, Hobeika, Elias, Reth, Michael, Huber, Lukas A., Krueger, Andreas, Klein, Christoph
Publicado no Front Immunol (2019)

The E3 ubiquitin ligase UBR5 interacts with TTC7A and may be associated with very early onset inflammatory bowel disease

Por Dhingani, Neel, Guo, Conghui, Pan, Jie, Li, Qi, Warner, Neil, Jardine, Sasha, Leung, Gabriella, Kotlarz, Daniel, Gonzaga-Jauregui, Claudia, Klein, Christoph, Snapper, Scott B., Navas-López, Víctor Manuel, Muise, Aleixo M.
Publicado no Sci Rep (2020)

The phenotype of human STK4 deficiency

Por Abdollahpour, Hengameh, Appaswamy, Giridharan, Kotlarz, Daniel, Diestelhorst, Jana, Beier, Rita, Schäffer, Alejandro A., Gertz, E. Michael, Schambach, Axel, Kreipe, Hans H., Pfeifer, Dietmar, Engelhardt, Karin R., Rezaei, Nima, Grimbacher, Bodo, Lohrmann, Sabine, Sherkat, Roya, Klein, Christoph
Publicado em 2012

Drug Screen Identifies Leflunomide for Treatment of Inflammatory Bowel Diseases Caused by TTC7A Deficiency

Por Jardine, Sasha, Anderson, Sierra, Babcock, Stephen, Leung, Gabriella, Pan, Jie, Dhingani, Neel, Warner, Neil, Guo, Conghui, Siddiqui, Iram, Kotlarz, Daniel, Dowling, James J, Melnyk, Roman, Snapper, Scott B, Klein, Christoph, Thiagarajah, Jay R, Muise, Aleixo M
Publicado no Gastroenterology (2019)

Impaired IL-12- and IL-23-Mediated Immunity due to IL-12Rβ1 deficiency in Iranian Patients with Mendelian Susceptibility to Mycobacterial Disease

Por Nekooie-Marnany, Nioosha, Deswarte, Caroline, Ostadi, Vajiheh, Bagherpour, Bahram, Taleby, Elaheh, Ganjalikhani Hakemi, Mazdak, Voyer, Tom Le, Rahimi, Hamid, Rosain, Jérémie, Pourmoghadas, Zahra, Sheikhbahaei, Saba, Khoshnevisan, Razieh, Petersheim, Daniel, Kotlarz, Daniel, Klein, Christoph, Boisson-Dupuis, Stéphanie, Casanova, Jean-Laurent, Bustamante, Jacinta, Sherkat, Roya
Publicado no J Clin Immunol (2018)

NOX1 Regulates Collective and Planktonic Cell Migration: Insights From Patients With Pediatric-Onset IBD and NOX1 Deficiency

Por Khoshnevisan, Razieh, Anderson, Michael, Babcock, Stephen, Anderson, Sierra, Illig, David, Marquardt, Benjamin, Sherkat, Roya, Schröder, Katrin, Moll, Franziska, Hollizeck, Sebastian, Rohlfs, Meino, Walz, Christoph, Adibi, Peyman, Rezaei, Abbas, Andalib, Alireza, Koletzko, Sibylle, Muise, Aleixo M, Snapper, Scott B, Klein, Christoph, Thiagarajah, Jay R, Kotlarz, Daniel
Publicado no Inflamm Bowel Dis (2020)

Novel CARMIL2 loss-of-function variants are associated with pediatric inflammatory bowel disease

Por Bosa, Luca, Batura, Vritika, Colavito, Davide, Fiedler, Karoline, Gaio, Paola, Guo, Conghui, Li, Qi, Marzollo, Antonio, Mescoli, Claudia, Nambu, Ryusuke, Pan, Jie, Perilongo, Giorgio, Warner, Neil, Zhang, Shiqi, Kotlarz, Daniel, Klein, Christoph, Snapper, Scott B., Walters, Thomas D., Leon, Alberta, Griffiths, Anne M., Cananzi, Mara, Muise, Aleixo M.
Publicado no Sci Rep (2021)

Very Early Onset Inflammatory Bowel Disease: A Clinical Approach With a Focus on the Role of Genetics and Underlying Immune Deficiencies

Por Ouahed, Jodie, Spencer, Elizabeth, Kotlarz, Daniel, Shouval, Dror S, Kowalik, Matthew, Peng, Kaiyue, Field, Michael, Grushkin-Lerner, Leslie, Pai, Sung-Yun, Bousvaros, Athos, Cho, Judy, Argmann, Carmen, Schadt, Eric, Mcgovern, Dermot P B, Mokry, Michal, Nieuwenhuis, Edward, Clevers, Hans, Powrie, Fiona, Uhlig, Holm, Klein, Christoph, Muise, Aleixo, Dubinsky, Marla, Snapper, Scott B
Publicado no Inflamm Bowel Dis (2020)

FOXP3(+) Tregs require WASP to restrain Th2-mediated food allergy

Por Lexmond, Willem S., Goettel, Jeremy A., Lyons, Jonathan J., Jacobse, Justin, Deken, Marion M., Lawrence, Monica G., DiMaggio, Thomas H., Kotlarz, Daniel, Garabedian, Elizabeth, Sackstein, Paul, Nelson, Celeste C., Jones, Nina, Stone, Kelly D., Candotti, Fabio, Rings, Edmond H.H.M., Thrasher, Adrian J., Milner, Joshua D., Snapper, Scott B., Fiebiger, Edda
Publicado no J Clin Invest (2016)

Low-Dose Interleukin-2 Ameliorates Colitis in a Preclinical Humanized Mouse Model

Por Goettel, Jeremy A., Kotlarz, Daniel, Emani, Rohini, Canavan, James B., Konnikova, Liza, Illig, David, Frei, Sandra M., Field, Michael, Kowalik, Matthew, Peng, Kaiyue, Gringauz, Jordan, Mitsialis, Vanessa, Wall, Sarah M., Tsou, Amy, Griffith, Alexandra E., Huang, Ying, Friedman, Joshua R., Towne, Jennifer E., Plevy, Scott E., O’Hara Hall, Aisling, Snapper, Scott B.
Publicado no Cell Mol Gastroenterol Hepatol (2019)

Human TGF-β1 deficiency causes severe inflammatory bowel disease and encephalopathy

Por Kotlarz, Daniel, Marquardt, Benjamin, Barøy, Tuva, Lee, Way S., Konnikova, Liza, Hollizeck, Sebastian, Magg, Thomas, Lehle, Anna S., Walz, Christoph, Borggraefe, Ingo, Hauck, Fabian, Bufler, Philip, Conca, Raffaele, Wall, Sarah M., Schumacher, Eva M., Misceo, Doriana, Frengen, Eirik, Bentsen, Beint S., Uhlig, Holm H., Hopfner, Karl-Peter, Muise, Aleixo M., Snapper, Scott B., Strømme, Petter, Klein, Christoph
Publicado no Nat Genet (2018)

Inherited biallelic CSF3R mutations in severe congenital neutropenia

Por Triot, Alexa, Järvinen, Päivi M., Arostegui, Juan I., Murugan, Dhaarini, Kohistani, Naschla, Dapena Díaz, José Luis, Racek, Tomas, Puchałka, Jacek, Gertz, E. Michael, Schäffer, Alejandro A., Kotlarz, Daniel, Pfeifer, Dietmar, Díaz de Heredia Rubio, Cristina, Ozdemir, Mehmet Akif, Patiroglu, Turkan, Karakukcu, Musa, Sánchez de Toledo Codina, José, Yagüe, Jordi, Touw, Ivo P., Unal, Ekrem, Klein, Christoph
Publicado em 2014

CARMIL2 Deficiency Presenting as Very Early Onset Inflammatory Bowel Disease

Por Magg, Thomas, Shcherbina, Anna, Arslan, Duran, Desai, Mukesh M, Wall, Sarah, Mitsialis, Vanessa, Conca, Raffaele, Unal, Ekrem, Karacabey, Neslihan, Mukhina, Anna, Rodina, Yulia, Taur, Prasad D, Illig, David, Marquardt, Benjamin, Hollizeck, Sebastian, Jeske, Tim, Gothe, Florian, Schober, Tilmann, Rohlfs, Meino, Koletzko, Sibylle, Lurz, Eberhard, Muise, Aleixo M, Snapper, Scott B, Hauck, Fabian, Klein, Christoph, Kotlarz, Daniel
Publicado no Inflamm Bowel Dis (2019)

Inflammatory Bowel Disease and Mutations Affecting the Interleukin-10 Receptor

Por Glocker, Erik-Oliver, Kotlarz, Daniel, Boztug, Kaan, Gertz, E. Michael, Schäffer, Alejandro A., Noyan, Fatih, Perro, Mario, Diestelhorst, Jana, Allroth, Anna, Murugan, Dhaarini, Hätscher, Nadine, Pfeifer, Dietmar, Sykora, Karl-Walter, Sauer, Martin, Kreipe, Hans, Lacher, Martin, Nustede, Rainer, Woellner, Cristina, Baumann, Ulrich, Salzer, Ulrich, Koletzko, Sibylle, Shah, Neil, Segal, Anthony W., Sauerbrey, Axel, Buderus, Stephan, Snapper, Scott B., Grimbacher, Bodo, Klein, Christoph
Publicado em 2009

Loss-of-function mutations in the IL-21 receptor gene cause a primary immunodeficiency syndrome

Por Kotlarz, Daniel, Ziętara, Natalia, Uzel, Gulbu, Weidemann, Thomas, Braun, Christian J., Diestelhorst, Jana, Krawitz, Peter M., Robinson, Peter N., Hecht, Jochen, Puchałka, Jacek, Gertz, E. Michael, Schäffer, Alejandro A., Lawrence, Monica G., Kardava, Lela, Pfeifer, Dietmar, Baumann, Ulrich, Pfister, Eva-Doreen, Hanson, Eric P., Schambach, Axel, Jacobs, Roland, Kreipe, Hans, Moir, Susan, Milner, Joshua D., Schwille, Petra, Mundlos, Stefan, Klein, Christoph
Publicado em 2013

Prevalence and Clinical Features of Inflammatory Bowel Diseases Associated with Monogenic Variants, Identified by Whole-exome Sequencing in 1000 Children at a Single Center

Por Crowley, Eileen, Warner, Neil, Pan, Jie, Khalouei, Sam, Elkadri, Abdul, Fiedler, Karoline, Foong, Justin, Turinsky, Andrei L., Bronte-Tinkew, Dana, Zhang, Shiqi, Hu, Jamie, Tian, David, Li, Dalin, Horowitz, Julie, Siddiqui, Iram, Upton, Julia, Roifman, Chaim M., Church, Peter C., Wall, Donna A., Ramani, Arun K., Kotlarz, Daniel, Klein, Christoph, Uhlig, Holm, Snapper, Scott B., Gonzaga-Jauregui, Claudia, Paterson, Andrew, McGovern, Dermot PB., Brudno, Michael, Walters, Thomas D., Griffiths, Anne M., Muise, Aleixo M.
Publicado no Gastroenterology (2020)