The IL-23/T17 pathogenic axis in psoriasis is amplified by keratinocyte responses

door Lowes, Michelle A., Russell, Chris B., Martin, David A., Towne, Jennifer E., Krueger, James G.
Gepubliceerd in 2013

Interleukin-36 (IL-36) Ligands Require Processing for Full Agonist (IL-36α, IL-36β, and IL-36γ) or Antagonist (IL-36Ra) Activity

door Towne, Jennifer E., Renshaw, Blair R., Douangpanya, Jason, Lipsky, Brian P., Shen, Min, Gabel, Christopher A., Sims, John E.
Gepubliceerd in 2011

The Emerging Role of Interleukin-17 in the Pathogenesis of Psoriasis: Preclinical and Clinical Findings

door Martin, David A., Towne, Jennifer E., Kricorian, Gregory, Klekotka, Paul, Gudjonsson, Johann E., Krueger, James G., Russell, Chris B.
Gepubliceerd in 2012

The severity of experimental arthritis is independent of IL-36 receptor signaling

door Lamacchia, Céline, Palmer, Gaby, Rodriguez, Emiliana, Martin, Praxedis, Vigne, Solenne, Seemayer, Christian A, Talabot-Ayer, Dominique, Towne, Jennifer E, Gabay, Cem
Gepubliceerd in 2013

Opposing roles for IL-23 and IL-12 in maintaining occult cancer in an equilibrium state

door Teng, Michele W. L., Vesely, Matthew D., Duret, Helene, McLaughlin, Nicole, Towne, Jennifer E., Schreiber, Robert D., Smyth, Mark J.
Gepubliceerd in Cancer Res (2012)

Opposing activities of two novel members of the IL-1 ligand family regulate skin inflammation

door Blumberg, Hal, Dinh, Huyen, Trueblood, Esther S., Pretorius, James, Kugler, David, Weng, Ning, Kanaly, Suzanne T., Towne, Jennifer E., Willis, Cynthia R., Kuechle, Melanie K., Sims, John E., Peschon, Jacques J.
Gepubliceerd in 2007

Aquaporin 5-deficient mouse lungs are hyperresponsive to cholinergic stimulation

door Krane, Carissa M., Fortner, Christopher N., Hand, Arthur R., McGraw, Dennis W., Lorenz, John N., Wert, Susan E., Towne, Jennifer E., Paul, Richard J., Whitsett, Jeffrey A., Menon, Anil G.
Gepubliceerd in 2001

The CSF-1-receptor inhibitor, JNJ-40346527 (PRV-6527), reduced inflammatory macrophage recruitment to the intestinal mucosa and suppressed murine T cell mediated colitis

door Manthey, Carl L., Moore, Beverley A., Chen, Yanqing, Loza, Matthew J., Yao, Xiang, Liu, Hao, Belkowski, Stanley M., Raymond-Parks, Holly, Dunford, Paul J., Leon, Francisco, Towne, Jennifer E., Plevy, Scott E.
Gepubliceerd in PLoS One (2019)

QRICH1 Dictates the Outcome of ER Stress through Transcriptional Control of Proteostasis

door You, Kwontae, Wang, Lingfei, Chou, Chih-Hung, Liu, Kai, Nakata, Toru, Jaiswal, Alok, Yao, Junmei, Lefkovith, Ariel, Omar, Abdifatah, Perrigoue, Jacqueline G., Towne, Jennifer E., Regev, Aviv, Graham, Daniel B., Xavier, Ramnik J.
Gepubliceerd in Science (2021)

Abnormal Small Intestinal Epithelial Microvilli in Patients With Crohn’s Disease

door VanDussen, Kelli L., Stojmirović, Aleksandar, Li, Katherine, Liu, Ta-Chiang, Kimes, Patrick K., Muegge, Brian D., Simpson, Katherine F., Ciorba, Matthew A., Perrigoue, Jacqueline G., Friedman, Joshua R., Towne, Jennifer E., Head, Richard D., Stappenbeck, Thaddeus S.
Gepubliceerd in Gastroenterology (2018)

Differing roles for short chain fatty acids and GPR43 agonism in the regulation of intestinal barrier function and immune responses

door D’Souza, Warren N., Douangpanya, Jason, Mu, Sharon, Jaeckel, Peter, Zhang, Ming, Maxwell, Joseph R., Rottman, James B., Labitzke, Katja, Willee, Angela, Beckmann, Holger, Wang, Yingcai, Li, Yang, Schwandner, Ralf, Johnston, James A., Towne, Jennifer E., Hsu, Hailing
Gepubliceerd in PLoS One (2017)

IL-36 receptor promotes resolution of intestinal damage

door Medina-Contreras, Oscar, Harusato, Akihito, Nishio, Hikaru, Flannigan, Kyle L., Ngo, Vu, Leoni, Giovanna, Neumann, Philipp-Alexander, Geem, Duke, Lili, Loukia N., Ramadas, Ravisankar A., Chassaing, Benoit, Gewirtz, Andrew T., Kohlmeier, Jacob E., Parkos, Charles A., Towne, Jennifer E., Nusrat, Asma, Denning, Timothy L.
Gepubliceerd in J Immunol (2015)

Low-Dose Interleukin-2 Ameliorates Colitis in a Preclinical Humanized Mouse Model

door Goettel, Jeremy A., Kotlarz, Daniel, Emani, Rohini, Canavan, James B., Konnikova, Liza, Illig, David, Frei, Sandra M., Field, Michael, Kowalik, Matthew, Peng, Kaiyue, Gringauz, Jordan, Mitsialis, Vanessa, Wall, Sarah M., Tsou, Amy, Griffith, Alexandra E., Huang, Ying, Friedman, Joshua R., Towne, Jennifer E., Plevy, Scott E., O’Hara Hall, Aisling, Snapper, Scott B.
Gepubliceerd in Cell Mol Gastroenterol Hepatol (2019)