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The IL-23/T17 pathogenic axis in psoriasis is amplified by keratinocyte responses

Psoriasis is a complex inflammatory process resulting from activation of the well-defined IL-23/T17 cytokine axis. We review the role of key cytokines interleukin (IL)-17 and IL-23 in psoriasis, as well as tumor necrosis factor alpha (TNα), focusing on therapeutic cytokine interventions and what the...

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Detalhes bibliográficos
Main Authors: Lowes, Michelle A., Russell, Chris B., Martin, David A., Towne, Jennifer E., Krueger, James G.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3721313/
https://ncbi.nlm.nih.gov/pubmed/23291100
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.it.2012.11.005
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