Inflammatory Bowel Disease and Mutations Affecting the Interleukin-10 Receptor

BACKGROUND: The molecular cause of inflammatory bowel disease is largely unknown. METHODS: We performed genetic-linkage analysis and candidate-gene sequencing on samples from two unrelated consanguineous families with children who were affected by early-onset inflammatory bowel disease. We screened...

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Autori principali: Glocker, Erik-Oliver, Kotlarz, Daniel, Boztug, Kaan, Gertz, E. Michael, Schäffer, Alejandro A., Noyan, Fatih, Perro, Mario, Diestelhorst, Jana, Allroth, Anna, Murugan, Dhaarini, Hätscher, Nadine, Pfeifer, Dietmar, Sykora, Karl-Walter, Sauer, Martin, Kreipe, Hans, Lacher, Martin, Nustede, Rainer, Woellner, Cristina, Baumann, Ulrich, Salzer, Ulrich, Koletzko, Sibylle, Shah, Neil, Segal, Anthony W., Sauerbrey, Axel, Buderus, Stephan, Snapper, Scott B., Grimbacher, Bodo, Klein, Christoph
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2009
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2787406/
https://ncbi.nlm.nih.gov/pubmed/19890111
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1056/NEJMoa0907206
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