IL-12Rβ1 deficiency corresponding to concurrency of two diseases, mendelian susceptibility to mycobacterial disease and Crohn's disease

BACKGROUND: The interleukin-12 receptor β1 (IL-12Rβ1) deficiency is a primary immunodeficiency (PID), affecting the immunological pathway of interleukin 12/interferon- γ (IL12/IFN-γ) axis and interleukin 23 receptor (IL23R). Defect in this pathway is mainly affecting the cellular immunity-related di...

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發表在:J Clin Tuberc Other Mycobact Dis
Main Authors: Khoshnevisan, Razieh, Nekooei-marnany, Nioosha, Klein, Christoph, Kotlarz, Daniel, Behnam, Mahdieh, Ostadi, Vajihe, Yaran, Majid, Rezaei, Abbas, Sherkat, Roya
格式: Artigo
語言:Inglês
出版: Elsevier 2019
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Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6879969/
https://ncbi.nlm.nih.gov/pubmed/31788565
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jctube.2019.100123
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