FOXP3(+) Tregs require WASP to restrain Th2-mediated food allergy

In addition to the infectious consequences of immunodeficiency, patients with Wiskott-Aldrich syndrome (WAS) often suffer from poorly understood exaggerated immune responses that result in autoimmunity and elevated levels of serum IgE. Here, we have shown that WAS patients and mice deficient in WAS...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Lexmond, Willem S., Goettel, Jeremy A., Lyons, Jonathan J., Jacobse, Justin, Deken, Marion M., Lawrence, Monica G., DiMaggio, Thomas H., Kotlarz, Daniel, Garabedian, Elizabeth, Sackstein, Paul, Nelson, Celeste C., Jones, Nina, Stone, Kelly D., Candotti, Fabio, Rings, Edmond H.H.M., Thrasher, Adrian J., Milner, Joshua D., Snapper, Scott B., Fiebiger, Edda
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5096801/
https://ncbi.nlm.nih.gov/pubmed/27643438
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI85129
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