Elevated levels of leukotriene C(4) synthase mRNA distinguish a subpopulation of eosinophilic oesophagitis patients

BACKGROUND: Cysteinyl leukotrienes contribute to Th2-type inflammatory immune responses. Their levels in oesophageal tissue, however, do not distinguish patients with eosinophilic oesophagitis (EoE) from controls. OBJECTIVE: We asked whether mRNA levels of leukotriene C(4) synthase (LTC(4)S), a key...

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Detalhes bibliográficos
Main Authors: Lexmond, Willem S., Pardo, Michael, Rooney, Katharine, Goettel, Jeremy A., Snapper, Scott B., Yen, Elizabeth H., Dehlink, Eleonora, Nurko, Samuel, Fiebiger, Edda
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3728707/
https://ncbi.nlm.nih.gov/pubmed/23889244
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cea.12146
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