Activating Mutations of N-WASP Alter Shigella Pathogenesis

The pathogenesis of Shigella requires binding to the host protein NWASP. To examine the roles of structural conformation and phospho-regulation of NWASP during Shigella pathogenesis, mutant NWASP constructs predicted to result in a constitutively open conformation (L229P and L232P) or either a phosp...

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Bibliographische Detailangaben
Hauptverfasser: Adamovich, David A., Nakamura, Fumihiko, Worth, Austen, Burns, Siobhan, Thrasher, Adrian J., Hartwig, John H., Snapper, Scott B.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2009
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2697925/
https://ncbi.nlm.nih.gov/pubmed/19379711
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2009.04.050
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