Phosphorylation of WASp is a key regulator of activity and stability in vivo

The Wiskott-Aldrich syndrome protein (WASp) is a key cytoskeletal regulator in hematopoietic cells. Covalent modification of a conserved tyrosine by phosphorylation has emerged as an important potential determinant of activity, although the physiological significance remains uncertain. In a murine k...

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Главные авторы: Blundell, Michael P., Bouma, Gerben, Metelo, Joao, Worth, Austen, Calle, Yolanda, Cowell, Lucy A., Westerberg, Lisa S., Moulding, Dale A., Mirando, Samuel, Kinnon, Christine, Cory, Giles O., Jones, Gareth E., Snapper, Scott B., Burns, Siobhan O., Thrasher, Adrian J.
Формат: Artigo
Язык:Inglês
Опубликовано: National Academy of Sciences 2009
Предметы:
Biological Sciences
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2736139/
https://ncbi.nlm.nih.gov/pubmed/19805221
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0904346106
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