Φορτώνει......
Unregulated actin polymerization by WASp causes defects of mitosis and cytokinesis in X-linked neutropenia
Specific mutations in the human gene encoding the Wiskott-Aldrich syndrome protein (WASp) that compromise normal auto-inhibition of WASp result in unregulated activation of the actin-related protein 2/3 complex and increased actin polymerizing activity. These activating mutations are associated with...
Αποθηκεύτηκε σε:
| Κύριοι συγγραφείς: | , , , , , , , , , , , |
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| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
The Rockefeller University Press
2007
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2118706/ https://ncbi.nlm.nih.gov/pubmed/17724125 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20062324 |
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