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Tyrosine phosphorylation of WASP promotes calpain-mediated podosome disassembly

Podosomes are actin-based adhesions involved in migration of cells that have to cross tissue boundaries such as myeloid cells. The Wiskott Aldrich Syndrome Protein regulates de novo actin polymerization during podosome formation and it is cleaved by the protease calpain during podosome disassembly....

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Detalhes bibliográficos
Main Authors: Macpherson, Lee, Monypenny, James, Blundell, Michael P., Cory, Giles O., Tomé-García, Jessica, Thrasher, Adrian J., Jones, Gareth E., Calle, Yolanda
Formato: Artigo
Idioma:Inglês
Publicado em: Ferrata Storti Foundation 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3342969/
https://ncbi.nlm.nih.gov/pubmed/22133775
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2011.048868
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