Tyrosine phosphorylation of WASP promotes calpain-mediated podosome disassembly

Podosomes are actin-based adhesions involved in migration of cells that have to cross tissue boundaries such as myeloid cells. The Wiskott Aldrich Syndrome Protein regulates de novo actin polymerization during podosome formation and it is cleaved by the protease calpain during podosome disassembly....

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Bibliografiske detaljer
Main Authors: Macpherson, Lee, Monypenny, James, Blundell, Michael P., Cory, Giles O., Tomé-García, Jessica, Thrasher, Adrian J., Jones, Gareth E., Calle, Yolanda
Format: Artigo
Sprog:Inglês
Udgivet: Ferrata Storti Foundation 2012
Fag:
Original Articles and Brief Reports
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3342969/
https://ncbi.nlm.nih.gov/pubmed/22133775
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2011.048868
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