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Tyrosine phosphorylation of WASP promotes calpain-mediated podosome disassembly
Podosomes are actin-based adhesions involved in migration of cells that have to cross tissue boundaries such as myeloid cells. The Wiskott Aldrich Syndrome Protein regulates de novo actin polymerization during podosome formation and it is cleaved by the protease calpain during podosome disassembly....
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Ferrata Storti Foundation
2012
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3342969/ https://ncbi.nlm.nih.gov/pubmed/22133775 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2011.048868 |
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