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Tyrosine phosphorylation of WASP promotes calpain-mediated podosome disassembly

Podosomes are actin-based adhesions involved in migration of cells that have to cross tissue boundaries such as myeloid cells. The Wiskott Aldrich Syndrome Protein regulates de novo actin polymerization during podosome formation and it is cleaved by the protease calpain during podosome disassembly....

詳細記述

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書誌詳細
主要な著者: Macpherson, Lee, Monypenny, James, Blundell, Michael P., Cory, Giles O., Tomé-García, Jessica, Thrasher, Adrian J., Jones, Gareth E., Calle, Yolanda
フォーマット: Artigo
言語:Inglês
出版事項: Ferrata Storti Foundation 2012
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3342969/
https://ncbi.nlm.nih.gov/pubmed/22133775
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2011.048868
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