FOXP3(+) Tregs require WASP to restrain Th2-mediated food allergy

In addition to the infectious consequences of immunodeficiency, patients with Wiskott-Aldrich syndrome (WAS) often suffer from poorly understood exaggerated immune responses that result in autoimmunity and elevated levels of serum IgE. Here, we have shown that WAS patients and mice deficient in WAS...

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Udgivet i:J Clin Invest
Main Authors: Lexmond, Willem S., Goettel, Jeremy A., Lyons, Jonathan J., Jacobse, Justin, Deken, Marion M., Lawrence, Monica G., DiMaggio, Thomas H., Kotlarz, Daniel, Garabedian, Elizabeth, Sackstein, Paul, Nelson, Celeste C., Jones, Nina, Stone, Kelly D., Candotti, Fabio, Rings, Edmond H.H.M., Thrasher, Adrian J., Milner, Joshua D., Snapper, Scott B., Fiebiger, Edda
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Clinical Investigation 2016
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5096801/
https://ncbi.nlm.nih.gov/pubmed/27643438
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI85129
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