Biochemical and immunological characterization of a novel monoclonal antibody against mouse leukotriene B(4) receptor 1

Por Sasaki, Fumiyuki, Koga, Tomoaki, Saeki, Kazuko, Okuno, Toshiaki, Kazuno, Saiko, Fujimura, Tsutomu, Ohkawa, Yasuyuki, Yokomizo, Takehiko
Publicado no PLoS One (2017)

Non-steroidal anti-inflammatory drug delays corneal wound healing by reducing production of 12-hydroxyheptadecatrienoic acid, a ligand for leukotriene B(4) receptor 2

Por Iwamoto, Satoshi, Koga, Tomoaki, Ohba, Mai, Okuno, Toshiaki, Koike, Masato, Murakami, Akira, Matsuda, Akira, Yokomizo, Takehiko
Publicado no Sci Rep (2017)

Nontypeable Haemophilus influenzae induces COX-2 and PGE2 expression in lung epithelial cells via activation of p38 MAPK and NF-kappa B

Por Xu, Feng, Xu, Zhihao, Zhang, Rong, Wu, Zuqun, Lim, Jae-Hyang, Koga, Tomoaki, Li, Jian-Dong, Shen, Huahao
Publicado em 2008

MEF/ELF4 transactivation by E2F1 is inhibited by p53

Por Taura, Manabu, Suico, Mary Ann, Fukuda, Ryosuke, Koga, Tomoaki, Shuto, Tsuyoshi, Sato, Takashi, Morino-Koga, Saori, Okada, Seiji, Kai, Hirofumi
Publicado em 2011

Mild Electrical Stimulation and Heat Shock Ameliorates Progressive Proteinuria and Renal Inflammation in Mouse Model of Alport Syndrome

Por Koga, Tomoaki, Kai, Yukari, Fukuda, Ryosuke, Morino-Koga, Saori, Suico, Mary Ann, Koyama, Kosuke, Sato, Takashi, Shuto, Tsuyoshi, Kai, Hirofumi
Publicado em 2012

Mild electrical stimulation with heat shock guides differentiation of embryonic stem cells into Pdx1-expressing cells within the definitive endoderm

Por Koga, Tomoaki, Shiraki, Nobuaki, Yano, Shuichiro, Suico, Mary Ann, Morino-Koga, Saori, Sato, Takashi, Shuto, Tsuyoshi, Kume, Shoen, Kai, Hirofumi
Publicado no BMC Biotechnol (2017)

Opposing roles of PAK2 and PAK4 in synergistic induction of MUC5AC mucin by bacterium NTHi and EGF

Por Huang, Yuxian, Mikami, Fumi, Jono, Hirofumi, Zhang, Wenhong, Weng, Xinhua, Koga, Tomoaki, Xu, Haidong, Yan, Chen, Kai, Hirofumi, Li, Jian-Dong
Publicado em 2007

Posttranslational negative regulation of glycosylated and non-glycosylated BCRP expression by Derlin-1

Por Sugiyama, Takashi, Shuto, Tsuyoshi, Suzuki, Shingo, Sato, Takashi, Koga, Tomoaki, Suico, Mary Ann, Kusuhara, Hiroyuki, Sugiyama, Yuichi, Cyr, Douglas M., Kai, Hirofumi
Publicado no Biochem Biophys Res Commun (2010)

Inhibition of PDE4B suppresses inflammation by increasing expression of the deubiquitinase CYLD

Por Komatsu, Kensei, Lee, Ji-Yun, Miyata, Masanori, Hyang Lim, Jae, Jono, Hirofumi, Koga, Tomoaki, Xu, Haidong, Yan, Chen, Kai, Hirofumi, Li, Jian-Dong
Publicado em 2013

Tumor Suppressor CYLD Acts as a Negative Regulator for Non-Typeable Haemophilus influenza-Induced Inflammation in the Middle Ear and Lung of Mice

Por Lim, Jae Hyang, Jono, Hirofumi, Koga, Tomoaki, Woo, Chang-Hoon, Ishinaga, Hajime, Bourne, Patricia, Xu, Haodong, Ha, Un-Hwan, Xu, Haidong, Li, Jian-Dong
Publicado em 2007

p53 Regulates Toll-Like Receptor 3 Expression and Function in Human Epithelial Cell Lines

Por Taura, Manabu, Eguma, Ayaka, Suico, Mary Ann, Shuto, Tsuyoshi, Koga, Tomoaki, Komatsu, Kensei, Komune, Takefumi, Sato, Takashi, Saya, Hideyuki, Li, Jian-Dong, Kai, Hirofumi
Publicado em 2008

Synergistic Activation of NF-κB by Nontypeable H. influenzae and S. pneumoniae Is Mediated by CK2, IKKβ-IκBα and p38 MAPK

Por Kweon, Soo-Mi, Wang, Beinan, Rixter, Davida, Lim, Jae Hyang, Koga, Tomoaki, Ishinaga, Hajime, Chen, Lin-Feng, Jono, Hirofumi, Xu, Haidong, Li, Jian-Dong
Publicado em 2006

12-hydroxyheptadecatrienoic acid promotes epidermal wound healing by accelerating keratinocyte migration via the BLT2 receptor

Por Liu, Min, Saeki, Kazuko, Matsunobu, Takehiko, Okuno, Toshiaki, Koga, Tomoaki, Sugimoto, Yukihiko, Yokoyama, Chieko, Nakamizo, Satoshi, Kabashima, Kenji, Narumiya, Shuh, Shimizu, Takao, Yokomizo, Takehiko
Publicado em 2014

Tumor Suppressor Cylindromatosis Acts as a Negative Regulator for Streptococcus pneumoniae-induced NFAT Signaling

Por Koga, Tomoaki, Lim, Jae Hyang, Jono, Hirofumi, Ha, Un Hwan, Xu, Haidong, Ishinaga, Hajime, Morino, Saori, Xu, Xiangbin, Yan, Chen, Kai, Hirofumi, Li, Jian-Dong
Publicado em 2008

Podocyte p53 Limits the Severity of Experimental Alport Syndrome

Por Fukuda, Ryosuke, Suico, Mary Ann, Kai, Yukari, Omachi, Kohei, Motomura, Keishi, Koga, Tomoaki, Komohara, Yoshihiro, Koyama, Kosuke, Yokota, Tsubasa, Taura, Manabu, Shuto, Tsuyoshi, Kai, Hirofumi
Publicado no J Am Soc Nephrol (2016)

TGF-β induces p65 acetylation to enhance bacteria-induced NF-κB activation

Por Ishinaga, Hajime, Jono, Hirofumi, Lim, Jae Hyang, Kweon, Soo-Mi, Xu, Haodong, Ha, Un-Hwan, Xu, Haidong, Koga, Tomoaki, Yan, Chen, Feng, Xin-Hua, Chen, Lin-Feng, Li, Jian-Dong
Publicado em 2007

Endoplasmic Reticulum (ER) Stress Induces Sirtuin 1 (SIRT1) Expression via the PI3K-Akt-GSK3β Signaling Pathway and Promotes Hepatocellular Injury

Por Koga, Tomoaki, Suico, Mary Ann, Shimasaki, Shogo, Watanabe, Eriko, Kai, Yukari, Koyama, Kosuke, Omachi, Kohei, Morino-Koga, Saori, Sato, Takashi, Shuto, Tsuyoshi, Mori, Kazutoshi, Hino, Shinjiro, Nakao, Mitsuyoshi, Kai, Hirofumi
Publicado no J Biol Chem (2015)

Leukotriene B(4) receptor type 2 protects against pneumolysin-dependent acute lung injury

Por Shigematsu, Misako, Koga, Tomoaki, Ishimori, Ayako, Saeki, Kazuko, Ishii, Yumiko, Taketomi, Yoshitaka, Ohba, Mai, Jo-Watanabe, Airi, Okuno, Toshiaki, Harada, Norihiro, Harayama, Takeshi, Shindou, Hideo, Li, Jian-Dong, Murakami, Makoto, Hoka, Sumio, Yokomizo, Takehiko
Publicado no Sci Rep (2016)

CYLD negatively regulates transforming growth factor-β-signalling via deubiquitinating Akt

Por Lim, Jae Hyang, Jono, Hirofumi, Komatsu, Kensei, Woo, Chang-Hoon, Lee, Jiyun, Miyata, Masanori, Matsuno, Takashi, Xu, Xiangbin, Huang, Yuxian, Zhang, Wenhong, Park, Soo Hyun, Kim, Yu-Il, Choi, Yoo-Duk, Shen, Huahao, Heo, Kyung-Sun, Xu, Haodong, Bourne, Patricia, Koga, Tomoaki, Xu, Haidong, Yan, Chen, Wang, Binghe, Chen, Lin-Feng, Feng, Xin-Hua, Li, Jian-Dong
Publicado em 2012