Mild electrical stimulation with heat shock guides differentiation of embryonic stem cells into Pdx1-expressing cells within the definitive endoderm

BACKGROUND: Because of the increasing number of diabetic patients, it is important to generate pancreatic and duodenal homeobox gene 1 (Pdx1)-expressing cells, which are capable of differentiating into pancreatic endocrine β cells. Mild electrical stimulation was reported to modulate the differentia...

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Detalhes bibliográficos
Publicado no:BMC Biotechnol
Main Authors: Koga, Tomoaki, Shiraki, Nobuaki, Yano, Shuichiro, Suico, Mary Ann, Morino-Koga, Saori, Sato, Takashi, Shuto, Tsuyoshi, Kume, Shoen, Kai, Hirofumi
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5312430/
https://ncbi.nlm.nih.gov/pubmed/28202025
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12896-017-0331-z
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