Leukotriene B(4) receptor type 2 protects against pneumolysin-dependent acute lung injury

Although pneumococcal infection is a serious problem worldwide and has a high mortality rate, the molecular mechanisms underlying the lethality caused by pneumococcus remain elusive. Here, we show that BLT2, a G protein-coupled receptor for leukotriene B(4) and 12(S)-hydroxyheptadecatrienoic acid (1...

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Vydáno v:Sci Rep
Hlavní autoři: Shigematsu, Misako, Koga, Tomoaki, Ishimori, Ayako, Saeki, Kazuko, Ishii, Yumiko, Taketomi, Yoshitaka, Ohba, Mai, Jo-Watanabe, Airi, Okuno, Toshiaki, Harada, Norihiro, Harayama, Takeshi, Shindou, Hideo, Li, Jian-Dong, Murakami, Makoto, Hoka, Sumio, Yokomizo, Takehiko
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2016
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5050523/
https://ncbi.nlm.nih.gov/pubmed/27703200
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep34560
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