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Non-steroidal anti-inflammatory drug delays corneal wound healing by reducing production of 12-hydroxyheptadecatrienoic acid, a ligand for leukotriene B(4) receptor 2

Non-steroidal anti-inflammatory drugs (NSAIDs) are widely used to reduce inflammation by suppressing cyclooxygenases (COXs). NSAID eye drops are frequently prescribed after ocular surgery to reduce inflammation and pain, but this treatment has clinically significant side effects, including corneal u...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Sci Rep
Hauptverfasser: Iwamoto, Satoshi, Koga, Tomoaki, Ohba, Mai, Okuno, Toshiaki, Koike, Masato, Murakami, Akira, Matsuda, Akira, Yokomizo, Takehiko
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5643301/
https://ncbi.nlm.nih.gov/pubmed/29038497
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-13122-8
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