12-hydroxyheptadecatrienoic acid promotes epidermal wound healing by accelerating keratinocyte migration via the BLT2 receptor

Leukotriene B(4) (LTB(4)) receptor type 2 (BLT2) is a G protein–coupled receptor (GPCR) for 12(S)-hydroxyheptadeca-5Z,8E,10E-trienoic acid (12-HHT) and LTB(4). Despite the well-defined proinflammatory roles of BLT1, the in vivo functions of BLT2 remain elusive. As mouse BLT2 is highly expressed in e...

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Detalhes bibliográficos
Main Authors: Liu, Min, Saeki, Kazuko, Matsunobu, Takehiko, Okuno, Toshiaki, Koga, Tomoaki, Sugimoto, Yukihiko, Yokoyama, Chieko, Nakamizo, Satoshi, Kabashima, Kenji, Narumiya, Shuh, Shimizu, Takao, Yokomizo, Takehiko
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4042643/
https://ncbi.nlm.nih.gov/pubmed/24821912
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20132063
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