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Thromboxane A synthase-independent production of 12-hydroxyheptadecatrienoic acid, a BLT2 ligand
12(S)-hydroxyheptadeca-5Z,8E,10E-trienoic acid (12-HHT) has long been considered a by-product of thromboxane A(2) (TxA(2)) biosynthesis with no biological activity. Recently, we reported 12-HHT to be an endogenous ligand for BLT2, a low-affinity leukotriene B(4) receptor. To delineate the biosynthet...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
The American Society for Biochemistry and Molecular Biology
2013
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3793602/ https://ncbi.nlm.nih.gov/pubmed/24009185 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M037754 |
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