Nontypeable Haemophilus influenzae induces COX-2 and PGE2 expression in lung epithelial cells via activation of p38 MAPK and NF-kappa B

BACKGROUND: Nontypeable Haemophilus influenzae (NTHi) is an important respiratory pathogen implicated as an infectious trigger in chronic obstructive pulmonary disease, but its molecular interaction with human lung epithelial cells remains unclear. Herein, we tested that the hypothesis that NTHi ind...

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Detalhes bibliográficos
Main Authors: Xu, Feng, Xu, Zhihao, Zhang, Rong, Wu, Zuqun, Lim, Jae-Hyang, Koga, Tomoaki, Li, Jian-Dong, Shen, Huahao
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2008
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2270828/
https://ncbi.nlm.nih.gov/pubmed/18237405
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1465-9921-9-16
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