A p38 MAPK-Mediated Alteration of COX-2/PGE(2) Regulates Immunomodulatory Properties in Human Mesenchymal Stem Cell Aging

Because human mesenchymal stem cells (hMSC) have profound immunomodulatory effects, many attempts have been made to use hMSCs in preclinical and clinical trials. For hMSCs to be used in therapy, a large population of hMSCs must be generated by in vitro expansion. However, the immunomodulatory change...

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Detalhes bibliográficos
Main Authors: Yu, Kyung-Rok, Lee, Jin Young, Kim, Hyung-Sik, Hong, In-Sun, Choi, Soon Won, Seo, Yoojin, Kang, Insung, Kim, Jae-Jun, Lee, Byung-Chul, Lee, SeungHee, Kurtz, Andreas, Seo, Kwang-Won, Kang, Kyung-Sun
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4121064/
https://ncbi.nlm.nih.gov/pubmed/25090227
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0102426
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