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p53 Regulates Toll-Like Receptor 3 Expression and Function in Human Epithelial Cell Lines
Toll-like receptors (TLRs) are important sensors of microbial pathogens and mediators of innate immune responses. Although the signal transduction of TLRs is well elucidated, their basal regulation is largely unexplored. Here we show that the tumor suppressor p53 positively regulates the transcripti...
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| Main Authors: | , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology (ASM)
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2573237/ https://ncbi.nlm.nih.gov/pubmed/18779317 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01202-08 |
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