Rb/E2F1 Regulates the Innate Immune Receptor Toll-Like Receptor 3 in Epithelial Cells

Tumor suppressor genes regulate the antiviral host defense through molecular mechanisms that are not yet well explored. Here, we show that the tumor suppressor retinoblastoma (Rb) protein positively regulates Toll-like receptor 3 (TLR3) expression, the sensing receptor for viral double-stranded RNA...

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Detalhes bibliográficos
Main Authors: Taura, Manabu, Suico, Mary Ann, Koyama, Kosuke, Komatsu, Kensei, Miyakita, Rui, Matsumoto, Chizuru, Kudo, Eriko, Kariya, Ryusho, Goto, Hiroki, Kitajima, Shunsuke, Takahashi, Chiaki, Shuto, Tsuyoshi, Nakao, Mitsuyoshi, Okada, Seiji, Kai, Hirofumi
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2012
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3318576/
https://ncbi.nlm.nih.gov/pubmed/22310660
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.06454-11
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