Opposing roles of PAK2 and PAK4 in synergistic induction of MUC5AC mucin by bacterium NTHi and EGF

Mucin, a major component of mucus, plays a critical role in host mucosal defense response by participating in mucociliary clearance. However, if overproduced, overproduced mucus leads to airway mucus obstruction and conductive hearing loss. Despite extensive studies that focus on investigating how M...

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Main Authors: Huang, Yuxian, Mikami, Fumi, Jono, Hirofumi, Zhang, Wenhong, Weng, Xinhua, Koga, Tomoaki, Xu, Haidong, Yan, Chen, Kai, Hirofumi, Li, Jian-Dong
Formato: Artigo
Idioma:Inglês
Publicado: 2007
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3345029/
https://ncbi.nlm.nih.gov/pubmed/17555715
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2007.05.170
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