Differential regulation of Streptococcus pneumoniae-induced human MUC5AC mucin expression through distinct MAPK pathways

Human epithelial mucin, the major glycoprotein component of mucus, plays a critical role in host innate defense response against invading microbes by facilitating the mucociliary clearance. Excess mucin production, however, overwhelms the mucociliary clearance, resulting in not only defective mucosa...

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Hlavní autoři: Lim, Jae Hyang, Kim, Hyun-Jung, Komatsu, Kensei, Ha, Unhwan, Huang, Yuxian, Jono, Hirofumi, Kweon, Soo-Mi, Lee, Jiyun, Xu, Xiangbin, Zhang, Gen-Sheng, Shen, Huahao, Kai, Hirofumi, Zhang, Wenhong, Xu, Haidong, Li, Jian-Dong
Médium: Artigo
Jazyk:Inglês
Vydáno: e-Century Publishing Corporation 2009
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Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2776328/
https://ncbi.nlm.nih.gov/pubmed/19956440
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