MKP1 Regulates the Induction of MUC5AC Mucin by Streptococcus pneumoniae Pneumolysin by Inhibiting the PAK4-JNK Signaling Pathway

Mucosal epithelial cells in the respiratory tract act as the first line of host innate defense against inhaled microbes by producing a range of molecules for clearance. In particular, epithelial mucins facilitate the mucociliary clearance by physically trapping the inhaled microbes. Up-regulation of...

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Bibliografiset tiedot
Päätekijät: Ha, Un-Hwan, Lim, Jae Hyang, Kim, Hyun-Joong, Wu, Weihui, Jin, Shouguang, Xu, Haidong, Li, Jian-Dong
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Biochemistry and Molecular Biology 2008
Aiheet:
Mechanisms of Signal Transduction
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2576563/
https://ncbi.nlm.nih.gov/pubmed/18782768
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M802519200
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