Loading...

Inhibition of PDE4B suppresses inflammation by increasing expression of the deubiquitinase CYLD

The deubiquitinase CYLD acts as a key negative regulator to tightly control overactive inflammation. Most anti-inflammatory strategies have focused on directly targeting the positive regulator, which often results in significant side effects such as suppression of the host defence response. Here, we...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Komatsu, Kensei, Lee, Ji-Yun, Miyata, Masanori, Hyang Lim, Jae, Jono, Hirofumi, Koga, Tomoaki, Xu, Haidong, Yan, Chen, Kai, Hirofumi, Li, Jian-Dong
Format: Artigo
Sprog:Inglês
Udgivet: Nature Pub. Group 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3644066/
https://ncbi.nlm.nih.gov/pubmed/23575688
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms2674
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!