Altered Gene Expression Associated with microRNA Binding Site Polymorphisms

od Võsa, Urmo, Esko, Tõnu, Kasela, Silva, Annilo, Tarmo
Wydane w PLoS One (2015)

CDH13 promoter SNPs with pleiotropic effect on cardiometabolic parameters represent methylation QTLs

od Putku, Margus, Kals, Mart, Inno, Rain, Kasela, Silva, Org, Elin, Kožich, Viktor, Milani, Lili, Laan, Maris
Wydane w Hum Genet (2014)

Integrative approach identifies SLC6A20 and CXCR6 as putative causal genes for the COVID-19 GWAS signal in the 3p21.31 locus

od Kasela, Silva, Daniloski, Zharko, Jordan, Tristan X., tenOever, Benjamin R., Sanjana, Neville E., Lappalainen, Tuuli
Wydane w medRxiv (2021)

Imprinted genes and imprinting control regions show predominant intermediate methylation in adult somatic tissues

od Pervjakova, Natalia, Kasela, Silva, Morris, Andrew P, Kals, Mart, Metspalu, Andres, Lindgren, Cecilia M, Salumets, Andres, Mägi, Reedik
Wydane w Epigenomics (2016)

Age-related profiling of DNA methylation in CD8+ T cells reveals changes in immune response and transcriptional regulator genes

od Tserel, Liina, Kolde, Raivo, Limbach, Maia, Tretyakov, Konstantin, Kasela, Silva, Kisand, Kai, Saare, Mario, Vilo, Jaak, Metspalu, Andres, Milani, Lili, Peterson, Pärt
Wydane w Sci Rep (2015)

Relationships between gut microbiota, plasma metabolites, and metabolic syndrome traits in the METSIM cohort

od Org, Elin, Blum, Yuna, Kasela, Silva, Mehrabian, Margarete, Kuusisto, Johanna, Kangas, Antti J., Soininen, Pasi, Wang, Zeneng, Ala-Korpela, Mika, Hazen, Stanley L., Laakso, Markku, Lusis, Aldons J.
Wydane w Genome Biol (2017)

Pathogenic implications for autoimmune mechanisms derived by comparative eQTL analysis of CD4(+) versus CD8(+) T cells

od Kasela, Silva, Kisand, Kai, Tserel, Liina, Kaleviste, Epp, Remm, Anu, Fischer, Krista, Esko, Tõnu, Westra, Harm-Jan, Fairfax, Benjamin P., Makino, Seiko, Knight, Julian C., Franke, Lude, Metspalu, Andres, Peterson, Pärt, Milani, Lili
Wydane w PLoS Genet (2017)

Identification of Required Host Factors for SARS-CoV-2 Infection in Human Cells

od Daniloski, Zharko, Jordan, Tristan X., Wessels, Hans-Hermann, Hoagland, Daisy A., Kasela, Silva, Legut, Mateusz, Maniatis, Silas, Mimitou, Eleni P., Lu, Lu, Geller, Evan, Danziger, Oded, Rosenberg, Brad R., Phatnani, Hemali, Smibert, Peter, Lappalainen, Tuuli, tenOever, Benjamin R., Sanjana, Neville E.
Wydane w Cell (2021)

Genetic and epigenetic regulation of gene expression in fetal and adult human livers

od Bonder, Marc Jan, Kasela, Silva, Kals, Mart, Tamm, Riin, Lokk, Kaie, Barragan, Isabel, Buurman, Wim A, Deelen, Patrick, Greve, Jan-Willem, Ivanov, Maxim, Rensen, Sander S, van Vliet-Ostaptchouk, Jana V, Wolfs, Marcel G, Fu, Jingyuan, Hofker, Marten H, Wijmenga, Cisca, Zhernakova, Alexandra, Ingelman-Sundberg, Magnus, Franke, Lude, Milani, Lili
Wydane w BMC Genomics (2014)

A genetics-led approach defines the drug target landscape of 30 immune-related traits

od Fang, Hai, De Wolf, Hans, Knezevic, Bogdan, Burnham, Katie L., Osgood, Julie, Sanniti, Anna, Lledó Lara, Alicia, Kasela, Silva, De Cesco, Stephane, Wegner, Jörg K., Handunnetthi, Lahiru, McCann, Fiona E., Chen, Liye, Sekine, Takuya, Brennan, Paul E., Marsden, Brian D., Damerell, David, O’Callaghan, Chris A., Bountra, Chas, Bowness, Paul, Sundström, Yvonne, Milani, Lili, Berg, Louise, Göhlmann, Hinrich W., Peeters, Pieter J., Fairfax, Benjamin P., Sundström, Michael, Knight, Julian C.
Wydane w Nat Genet (2019)

Cell type specific genetic regulation of gene expression across human tissues

od Kim-Hellmuth, Sarah, Aguet, François, Oliva, Meritxell, Muñoz-Aguirre, Manuel, Kasela, Silva, Wucher, Valentin, Castel, Stephane E., Hamel, Andrew R., Viñuela, Ana, Roberts, Amy L., Mangul, Serghei, Wen, Xiaoquan, Wang, Gao, Barbeira, Alvaro N., Garrido-Martín, Diego, Nadel, Brian, Zou, Yuxin, Bonazzola, Rodrigo, Quan, Jie, Brown, Andrew, Martinez-Perez, Angel, Soria, José Manuel, Getz, Gad, Dermitzakis, Emmanouil T., Small, Kerrin S., Stephens, Matthew, Xi, Hualin S., Im, Hae Kyung, Guigó, Roderic, Segrè, Ayellet V., Stranger, Barbara E., Ardlie, Kristin G., Lappalainen, Tuuli
Wydane w Science (2020)

The impact of sex on gene expression across human tissues

od Oliva, Meritxell, Muñoz-Aguirre, Manuel, Kim-Hellmuth, Sarah, Wucher, Valentin, Gewirtz, Ariel D. H., Cotter, Daniel J., Parsana, Princy, Kasela, Silva, Balliu, Brunilda, Viñuela, Ana, Castel, Stephane E., Mohammadi, Pejman, Aguet, François, Zou, Yuxin, Khramtsova, Ekaterina A., Skol, Andrew D., Garrido-Martín, Diego, Reverter, Ferran, Brown, Andrew, Evans, Patrick, Gamazon, Eric R., Payne, Anthony, Bonazzola, Rodrigo, Barbeira, Alvaro N., Hamel, Andrew R., Martinez-Perez, Angel, Manuel Soria, José, Consortium, GTEx, Pierce, Brandon L., Stephens, Matthew, Eskin, Eleazar, Dermitzakis, Emmanouil T., Segrè, Ayellet V., Kyung Im, Hae, Engelhardt, Barbara E., Ardlie, Kristin G., Montgomery, Stephen B., Battle, Alexis J., Lappalainen, Tuuli, Guigó, Roderic, Stranger, Barbara E.
Wydane w Science (2020)

Genetic and non-genetic factors affecting the expression of COVID-19-relevant genes in the large airway epithelium

od Kasela, Silva, Ortega, Victor E., Martorella, Molly, Garudadri, Suresh, Nguyen, Jenna, Ampleford, Elizabeth, Pasanen, Anu, Nerella, Srilaxmi, Buschur, Kristina L., Barjaktarevic, Igor Z., Barr, R. Graham, Bleecker, Eugene R., Bowler, Russell P., Comellas, Alejandro P., Cooper, Christopher B., Couper, David J., Criner, Gerard J., Curtis, Jeffrey L., Han, MeiLan K., Hansel, Nadia N., Hoffman, Eric A., Kaner, Robert J., Krishnan, Jerry A., Martinez, Fernando J., McDonald, Merry-Lynn N., Meyers, Deborah A., Paine, Robert, Peters, Stephen P., Castro, Mario, Denlinger, Loren C., Erzurum, Serpil C., Fahy, John V., Israel, Elliot, Jarjour, Nizar N., Levy, Bruce D., Li, Xingnan, Moore, Wendy C., Wenzel, Sally E., Zein, Joe, Langelier, Charles, Woodruff, Prescott G., Lappalainen, Tuuli, Christenson, Stephanie A.
Wydane w Genome Med (2021)

Cell Specific eQTL Analysis without Sorting Cells

od Westra, Harm-Jan, Arends, Danny, Esko, Tõnu, Peters, Marjolein J., Schurmann, Claudia, Schramm, Katharina, Kettunen, Johannes, Yaghootkar, Hanieh, Fairfax, Benjamin P., Andiappan, Anand Kumar, Li, Yang, Fu, Jingyuan, Karjalainen, Juha, Platteel, Mathieu, Visschedijk, Marijn, Weersma, Rinse K., Kasela, Silva, Milani, Lili, Tserel, Liina, Peterson, Pärt, Reinmaa, Eva, Hofman, Albert, Uitterlinden, André G., Rivadeneira, Fernando, Homuth, Georg, Petersmann, Astrid, Lorbeer, Roberto, Prokisch, Holger, Meitinger, Thomas, Herder, Christian, Roden, Michael, Grallert, Harald, Ripatti, Samuli, Perola, Markus, Wood, Andrew R., Melzer, David, Ferrucci, Luigi, Singleton, Andrew B., Hernandez, Dena G., Knight, Julian C., Melchiotti, Rossella, Lee, Bernett, Poidinger, Michael, Zolezzi, Francesca, Larbi, Anis, Wang, De Yun, van den Berg, Leonard H., Veldink, Jan H., Rotzschke, Olaf, Makino, Seiko, Salomaa, Veikko, Strauch, Konstantin, Völker, Uwe, van Meurs, Joyce B. J., Metspalu, Andres, Wijmenga, Cisca, Jansen, Ritsert C., Franke, Lude
Wydane w PLoS Genet (2015)

Association of maternal prenatal smoking GFI1-locus and cardio-metabolic phenotypes in 18,212 adults

od Parmar, Priyanka, Lowry, Estelle, Cugliari, Giovanni, Suderman, Matthew, Wilson, Rory, Karhunen, Ville, Andrew, Toby, Wiklund, Petri, Wielscher, Matthias, Guarrera, Simonetta, Teumer, Alexander, Lehne, Benjamin, Milani, Lili, de Klein, Niek, Mishra, Pashupati P., Melton, Phillip E., Mandaviya, Pooja R., Kasela, Silva, Nano, Jana, Zhang, Weihua, Zhang, Yan, Uitterlinden, Andre G., Peters, Annette, Schöttker, Ben, Gieger, Christian, Anderson, Denise, Boomsma, Dorret I., Grabe, Hans J., Panico, Salvatore, Veldink, Jan H., van Meurs, Joyce B.J., van den Berg, Leonard, Beilin, Lawrence J., Franke, Lude, Loh, Marie, van Greevenbroek, Marleen M.J., Nauck, Matthias, Kähönen, Mika, Hurme, Mikko A., Raitakari, Olli T., Franco, Oscar H., Slagboom, P.Eline, van der Harst, Pim, Kunze, Sonja, Felix, Stephan B., Zhang, Tao, Chen, Wei, Mori, Trevor A., Bonnefond, Amelie, Heijmans, Bastiaan T., Muka, Taulant, Kooner, Jaspal S., Fischer, Krista, Waldenberger, Melanie, Froguel, Philippe, Huang, Rae-Chi, Lehtimäki, Terho, Rathmann, Wolfgang, Relton, Caroline L., Matullo, Giuseppe, Brenner, Hermann, Verweij, Niek, Li, Shengxu, Chambers, John C., Järvelin, Marjo-Riitta, Sebert, Sylvain
Wydane w EBioMedicine (2018)

An epigenome-wide association study meta-analysis of educational attainment

od Karlsson Linnér, Richard, Marioni, Riccardo E, Rietveld, Cornelius A, Simpkin, Andrew J, Davies, Neil M, Watanabe, Kyoko, Armstrong, Nicola J, Auro, Kirsi, Baumbach, Clemens, Jan Bonder, Marc, Buchwald, Jadwiga, Fiorito, Giovanni, Ismail, Khadeeja, Iurato, Stella, Joensuu, Anni, Karell, Pauliina, Kasela, Silva, Lahti, Jari, McRae, Allan F, Mandaviya, Pooja R, Seppälä, Ilkka, Wang, Yunzhang, Baglietto, Laura, Binder, Elisabeth B, Harris, Sarah E, Hodge, Allison M, Horvath, Steve, Hurme, Mikko, Johannesson, Magnus, Latvala, Antti, Mather, Karen A, Medland, Sarah E, Metspalu, Andres, Milani, Lili, Milne, Roger L, Pattie, Alison, Pedersen, Nancy L, Peters, Annette, Polidoro, Silvia, Räikkönen, Katri, Severi, Gianluca, Starr, John M, Stolk, Lisette, Waldenberger, Melanie, Eriksson, Johan G, Esko, Tõnu, Franke, Lude, Gieger, Christian, Giles, Graham G, Hägg, Sara, Jousilahti, Pekka, Kaprio, Jaakko, Kähönen, Mika, Lehtimäki, Terho, Martin, Nicholas G, van Meurs, Joyce B C, Ollikainen, Miina, Perola, Markus, Posthuma, Danielle, Raitakari, Olli T, Sachdev, Perminder S, Taskesen, Erdogan, Uitterlinden, André G, Vineis, Paolo, Wijmenga, Cisca, Wright, Margaret J, Relton, Caroline, Davey Smith, George, Deary, Ian J, Koellinger, Philipp D, Benjamin, Daniel J
Wydane w Mol Psychiatry (2017)

Whole genome sequence analysis of pulmonary function and COPD in 19,996 multi-ethnic participants

od Zhao, Xutong, Qiao, Dandi, Yang, Chaojie, Kasela, Silva, Kim, Wonji, Ma, Yanlin, Shrine, Nick, Batini, Chiara, Sofer, Tamar, Taliun, Sarah A. Gagliano, Sakornsakolpat, Phuwanat, Balte, Pallavi P., Prokopenko, Dmitry, Yu, Bing, Lange, Leslie A., Dupuis, Josée, Cade, Brian E., Lee, Jiwon, Gharib, Sina A., Daya, Michelle, Laurie, Cecelia A., Ruczinski, Ingo, Cupples, L. Adrienne, Loehr, Laura R., Bartz, Traci M., Morrison, Alanna C., Psaty, Bruce M., Vasan, Ramachandran S., Wilson, James G., Taylor, Kent D., Durda, Peter, Johnson, W. Craig, Cornell, Elaine, Guo, Xiuqing, Liu, Yongmei, Tracy, Russell P., Ardlie, Kristin G., Aguet, François, VanDenBerg, David J., Papanicolaou, George J., Rotter, Jerome I., Barnes, Kathleen C., Jain, Deepti, Nickerson, Deborah A., Muzny, Donna M., Metcalf, Ginger A., Doddapaneni, Harshavardhan, Dugan-Perez, Shannon, Gupta, Namrata, Gabriel, Stacey, Rich, Stephen S., O’Connor, George T., Redline, Susan, Reed, Robert M., Laurie, Cathy C., Daviglus, Martha L., Preudhomme, Liana K., Burkart, Kristin M., Kaplan, Robert C., Wain, Louise V., Tobin, Martin D., London, Stephanie J., Lappalainen, Tuuli, Oelsner, Elizabeth C., Abecasis, Goncalo R., Silverman, Edwin K., Barr, R. Graham, Cho, Michael H., Manichaikul, Ani
Wydane w Nat Commun (2020)

Epigenome-wide association study of body mass index, and the adverse outcomes of adiposity

od Wahl, Simone, Drong, Alexander, Lehne, Benjamin, Loh, Marie, Scott, William R, Kunze, Sonja, Tsai, Pei-Chien, Ried, Janina S, Zhang, Weihua, Yang, Youwen, Tan, Sili, Fiorito, Giovanni, Franke, Lude, Guarrera, Simonetta, Kasela, Silva, Kriebel, Jennifer, Richmond, Rebecca C, Adamo, Marco, Afzal, Uzma, Ala-Korpela, Mika, Albetti, Benedetta, Ammerpohl, Ole, Apperley, Jane F, Beekman, Marian, Bertazzi, Pier Alberto, Black, S. Lucas, Blancher, Christine, Bonder, Marc-Jan, Brosch, Mario, Carstensen-Kirberg, Maren, De Craen, Anton J.M., de Lusignan, Simon, Dehghan, Abbas, Elkalaawy, Mohamed, Fischer, Krista, Franco, Oscar H., Gaunt, Tom R, Hampe, Jochen, Hashemi, Majid, Isaacs, Aaron, Jenkinson, Andrew, Jha, Sujeet, Kato, Norihiro, Krogh, Vittorio, Laffan, Michael, Meisinger, Christa, Meitinger, Thomas, Mok, Zuan Yu, Motta, Valeria, Ng, Hong Kiat, Nikolakopoulou, Zacharoula, Nteliopoulos, Georgios, Panico, Salvatore, Pervjakova, Natalia, Prokisch, Holger, Rathmann, Wolfgang, Roden, Michael, Rota, Federica, Rozario, Michelle Ann, Sandling, Johanna K, Schafmayer, Clemens, Schramm, Katharina, Siebert, Reiner, Slagboom, P Eline, Soininen, Pasi, Stolk, Lisette, Strauch, Konstantin, Tai, E-Shyong, Tarantini, Letizia, Thorand, Barbara, Tigchelaar, Ettje F, Tumino, Rosario, Uitterlinden, Andre G, van Duijn, Cornelia, van Meurs, Joyce BJ, Vineis, Paolo, Wickremasinghe, Ananda Rajitha, Wijmenga, Cisca, Yang, Tsun-Po, Yuan, Wei, Zhernakova, Alexandra, Batterham, Rachel L., Smith, George Davey, Deloukas, Panos, Heijmans, Bastiaan T, Herder, Christian, Hofman, Albert, Lindgren, Cecilia M, Milani, Lili, van der Harst, Pim, Peters, Annette, Illig, Thomas, Relton, Caroline L, Waldenberger, Melanie, Järvelin, Marjo-Riitta, Bollati, Valentina, Soong, Richie, Spector, Tim D, Scott, James, McCarthy, Mark I, Elliott, Paul, Bell, Jordana T, Matullo, Giuseppe, Gieger, Christian, Kooner, Jaspal S, Grallert, Harald, Chambers, John C
Wydane w Nature (2016)

Genome-wide association studies identify 137 genetic loci for DNA methylation biomarkers of aging

od McCartney, Daniel L., Min, Josine L., Richmond, Rebecca C., Lu, Ake T., Sobczyk, Maria K., Davies, Gail, Broer, Linda, Guo, Xiuqing, Jeong, Ayoung, Jung, Jeesun, Kasela, Silva, Katrinli, Seyma, Kuo, Pei-Lun, Matias-Garcia, Pamela R., Mishra, Pashupati P., Nygaard, Marianne, Palviainen, Teemu, Patki, Amit, Raffield, Laura M., Ratliff, Scott M., Richardson, Tom G., Robinson, Oliver, Soerensen, Mette, Sun, Dianjianyi, Tsai, Pei-Chien, van der Zee, Matthijs D., Walker, Rosie M., Wang, Xiaochuan, Wang, Yunzhang, Xia, Rui, Xu, Zongli, Yao, Jie, Zhao, Wei, Correa, Adolfo, Boerwinkle, Eric, Dugué, Pierre-Antoine, Durda, Peter, Elliott, Hannah R., Gieger, Christian, de Geus, Eco J. C., Harris, Sarah E., Hemani, Gibran, Imboden, Medea, Kähönen, Mika, Kardia, Sharon L. R., Kresovich, Jacob K., Li, Shengxu, Lunetta, Kathryn L., Mangino, Massimo, Mason, Dan, McIntosh, Andrew M., Mengel-From, Jonas, Moore, Ann Zenobia, Murabito, Joanne M., Ollikainen, Miina, Pankow, James S., Pedersen, Nancy L., Peters, Annette, Polidoro, Silvia, Porteous, David J., Raitakari, Olli, Rich, Stephen S., Sandler, Dale P., Sillanpää, Elina, Smith, Alicia K., Southey, Melissa C., Strauch, Konstantin, Tiwari, Hemant, Tanaka, Toshiko, Tillin, Therese, Uitterlinden, Andre G., Van Den Berg, David J., van Dongen, Jenny, Wilson, James G., Wright, John, Yet, Idil, Arnett, Donna, Bandinelli, Stefania, Bell, Jordana T., Binder, Alexandra M., Boomsma, Dorret I., Chen, Wei, Christensen, Kaare, Conneely, Karen N., Elliott, Paul, Ferrucci, Luigi, Fornage, Myriam, Hägg, Sara, Hayward, Caroline, Irvin, Marguerite, Kaprio, Jaakko, Lawlor, Deborah A., Lehtimäki, Terho, Lohoff, Falk W., Milani, Lili, Milne, Roger L., Probst-Hensch, Nicole, Reiner, Alex P., Ritz, Beate, Rotter, Jerome I., Smith, Jennifer A., Taylor, Jack A., van Meurs, Joyce B. J., Vineis, Paolo, Waldenberger, Melanie, Deary, Ian J., Relton, Caroline L., Horvath, Steve, Marioni, Riccardo E.
Wydane w Genome Biol (2021)

The transcriptional landscape of age in human peripheral blood

od Peters, Marjolein J., Joehanes, Roby, Pilling, Luke C., Schurmann, Claudia, Conneely, Karen N., Powell, Joseph, Reinmaa, Eva, Sutphin, George L., Zhernakova, Alexandra, Schramm, Katharina, Wilson, Yana A., Kobes, Sayuko, Tukiainen, Taru, Ramos, Yolande F., Göring, Harald H. H., Fornage, Myriam, Liu, Yongmei, Gharib, Sina A., Stranger, Barbara E., De Jager, Philip L., Aviv, Abraham, Levy, Daniel, Murabito, Joanne M., Munson, Peter J., Huan, Tianxiao, Hofman, Albert, Uitterlinden, André G., Rivadeneira, Fernando, van Rooij, Jeroen, Stolk, Lisette, Broer, Linda, Verbiest, Michael M. P. J., Jhamai, Mila, Arp, Pascal, Metspalu, Andres, Tserel, Liina, Milani, Lili, Samani, Nilesh J., Peterson, Pärt, Kasela, Silva, Codd, Veryan, Peters, Annette, Ward-Caviness, Cavin K., Herder, Christian, Waldenberger, Melanie, Roden, Michael, Singmann, Paula, Zeilinger, Sonja, Illig, Thomas, Homuth, Georg, Grabe, Hans-Jörgen, Völzke, Henry, Steil, Leif, Kocher, Thomas, Murray, Anna, Melzer, David, Yaghootkar, Hanieh, Bandinelli, Stefania, Moses, Eric K., Kent, Jack W., Curran, Joanne E., Johnson, Matthew P., Williams-Blangero, Sarah, Westra, Harm-Jan, McRae, Allan F., Smith, Jennifer A., Kardia, Sharon L. R., Hovatta, Iiris, Perola, Markus, Ripatti, Samuli, Salomaa, Veikko, Henders, Anjali K., Martin, Nicholas G., Smith, Alicia K., Mehta, Divya, Binder, Elisabeth B., Nylocks, K Maria, Kennedy, Elizabeth M., Klengel, Torsten, Ding, Jingzhong, Suchy-Dicey, Astrid M., Enquobahrie, Daniel A., Brody, Jennifer, Rotter, Jerome I., Chen, Yii-Der I., Houwing-Duistermaat, Jeanine, Kloppenburg, Margreet, Slagboom, P. Eline, Helmer, Quinta, den Hollander, Wouter, Bean, Shannon, Raj, Towfique, Bakhshi, Noman, Wang, Qiao Ping, Oyston, Lisa J., Psaty, Bruce M., Tracy, Russell P., Montgomery, Grant W., Turner, Stephen T., Blangero, John, Meulenbelt, Ingrid, Ressler, Kerry J., Yang, Jian, Franke, Lude, Kettunen, Johannes, Visscher, Peter M., Neely, G. Gregory, Korstanje, Ron, Hanson, Robert L., Prokisch, Holger, Ferrucci, Luigi, Esko, Tonu, Teumer, Alexander, van Meurs, Joyce B. J., Johnson, Andrew D.
Wydane w Nat Commun (2015)