Cell type specific genetic regulation of gene expression across human tissues

The Genotype-Tissue Expression (GTEx) project has identified expression and splicing quantitative trait loci in cis (QTLs) for the majority of genes across a wide range of human tissues. However, the functional characterization of these QTLs has been limited by the heterogeneous cellular composition...

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Publicado no:Science
Main Authors: Kim-Hellmuth, Sarah, Aguet, François, Oliva, Meritxell, Muñoz-Aguirre, Manuel, Kasela, Silva, Wucher, Valentin, Castel, Stephane E., Hamel, Andrew R., Viñuela, Ana, Roberts, Amy L., Mangul, Serghei, Wen, Xiaoquan, Wang, Gao, Barbeira, Alvaro N., Garrido-Martín, Diego, Nadel, Brian, Zou, Yuxin, Bonazzola, Rodrigo, Quan, Jie, Brown, Andrew, Martinez-Perez, Angel, Soria, José Manuel, Getz, Gad, Dermitzakis, Emmanouil T., Small, Kerrin S., Stephens, Matthew, Xi, Hualin S., Im, Hae Kyung, Guigó, Roderic, Segrè, Ayellet V., Stranger, Barbara E., Ardlie, Kristin G., Lappalainen, Tuuli
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8051643/
https://ncbi.nlm.nih.gov/pubmed/32913075
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aaz8528
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