RL-SKAT: An Exact and Efficient Score Test for Heritability and Set Tests

por Schweiger, Regev, Weissbrod, Omer, Rahmani, Elior, Müller-Nurasyid, Martina, Kunze, Sonja, Gieger, Christian, Waldenberger, Melanie, Rosset, Saharon, Halperin, Eran
Publicado en Genetics (2017)

Are Epigenetic Factors Implicated in Chronic Widespread Pain?

por Burri, Andrea, Marinova, Zoya, Robinson, Mark D., Kühnel, Brigitte, Waldenberger, Melanie, Wahl, Simone, Kunze, Sonja, Gieger, Christian, Livshits, Gregory, Williams, Frances
Publicado en PLoS One (2016)

Detecting heritable phenotypes without a model using fast permutation testing for heritability and set-tests

por Schweiger, Regev, Fisher, Eyal, Weissbrod, Omer, Rahmani, Elior, Müller-Nurasyid, Martina, Kunze, Sonja, Gieger, Christian, Waldenberger, Melanie, Rosset, Saharon, Halperin, Eran
Publicado en Nat Commun (2018)

The dynamics of smoking-related disturbed methylation: a two time-point study of methylation change in smokers, non-smokers and former smokers

por Wilson, Rory, Wahl, Simone, Pfeiffer, Liliane, Ward-Caviness, Cavin K., Kunze, Sonja, Kretschmer, Anja, Reischl, Eva, Peters, Annette, Gieger, Christian, Waldenberger, Melanie
Publicado en BMC Genomics (2017)

A genome-wide analysis of DNA methylation identifies a novel association signal for Lp(a) concentrations in the LPA promoter

por Coassin, Stefan, Hermann-Kleiter, Natascha, Haun, Margot, Wahl, Simone, Wilson, Rory, Paulweber, Bernhard, Kunze, Sonja, Meitinger, Thomas, Strauch, Konstantin, Peters, Annette, Waldenberger, Melanie, Kronenberg, Florian, Lamina, Claudia
Publicado en PLoS One (2020)

Genome-Wide Analysis of DNA Methylation and Fine Particulate Matter Air Pollution in Three Study Populations: KORA F3, KORA F4, and the Normative Aging Study

por Panni, Tommaso, Mehta, Amar J., Schwartz, Joel D., Baccarelli, Andrea A., Just, Allan C., Wolf, Kathrin, Wahl, Simone, Cyrys, Josef, Kunze, Sonja, Strauch, Konstantin, Waldenberger, Melanie, Peters, Annette
Publicado en Environ Health Perspect (2016)

Association between DNA Methylation in Whole Blood and Measures of Glucose Metabolism: KORA F4 Study

por Kriebel, Jennifer, Herder, Christian, Rathmann, Wolfgang, Wahl, Simone, Kunze, Sonja, Molnos, Sophie, Volkova, Nadezda, Schramm, Katharina, Carstensen-Kirberg, Maren, Waldenberger, Melanie, Gieger, Christian, Peters, Annette, Illig, Thomas, Prokisch, Holger, Roden, Michael, Grallert, Harald
Publicado en PLoS One (2016)

Novel DNA Methylation Sites Influence GPR15 Expression in Relation to Smoking

por Haase, Tina, Müller, Christian, Krause, Julia, Röthemeier, Caroline, Stenzig, Justus, Kunze, Sonja, Waldenberger, Melanie, Münzel, Thomas, Pfeiffer, Norbert, Wild, Philipp S., Michal, Matthias, Marini, Federico, Karakas, Mahir, Lackner, Karl J., Blankenberg, Stefan, Zeller, Tanja
Publicado en Biomolecules (2018)

Smoking-related changes in DNA methylation and gene expression are associated with cardio-metabolic traits

por Maas, Silvana C. E., Mens, Michelle M. J., Kühnel, Brigitte, van Meurs, Joyce B. J., Uitterlinden, André G., Peters, Annette, Prokisch, Holger, Herder, Christian, Grallert, Harald, Kunze, Sonja, Waldenberger, Melanie, Kavousi, Maryam, Kayser, Manfred, Ghanbari, Mohsen
Publicado en Clin Epigenetics (2020)

Prenatal and early life influences on epigenetic age in children: a study of mother–offspring pairs from two cohort studies

por Simpkin, Andrew J., Hemani, Gibran, Suderman, Matthew, Gaunt, Tom R., Lyttleton, Oliver, Mcardle, Wendy L., Ring, Susan M., Sharp, Gemma C., Tilling, Kate, Horvath, Steve, Kunze, Sonja, Peters, Annette, Waldenberger, Melanie, Ward-Caviness, Cavin, Nohr, Ellen A., Sørensen, Thorkild I. A., Relton, Caroline L., Smith, George Davey
Publicado en Hum Mol Genet (2016)

Anxiety Associated Increased CpG Methylation in the Promoter of Asb1: A Translational Approach Evidenced by Epidemiological and Clinical Studies and a Murine Model

por Emeny, Rebecca T, Baumert, Jens, Zannas, Anthony S, Kunze, Sonja, Wahl, Simone, Iurato, Stella, Arloth, Janine, Erhardt, Angelika, Balsevich, Georgia, Schmidt, Mathias V, Weber, Peter, Kretschmer, Anja, Pfeiffer, Liliane, Kruse, Johannes, Strauch, Konstantin, Roden, Michael, Herder, Christian, Koenig, Wolfgang, Gieger, Christian, Waldenberger, Melanie, Peters, Annette, Binder, Elisabeth B, Ladwig, Karl-Heinz
Publicado en Neuropsychopharmacology (2018)

Accelerated epigenetic aging as a risk factor for chronic obstructive pulmonary disease and decreased lung function in two prospective cohort studies

por Breen, Miyuki, Nwanaji-Enwerem, Jamaji C., Karrasch, Stefan, Flexeder, Claudia, Schulz, Holger, Waldenberger, Melanie, Kunze, Sonja, Ollert, Markus, Weidinger, Stefan, Colicino, Elena, Gao, Xu, Wang, Cuicui, Shen, Jincheng, Just, Allan C., Vokonas, Pantel, Sparrow, David, Hou, Lifang, Schwartz, Joel D., Baccarelli, Andrea A., Peters, Annette, Ward-Caviness, Cavin K.
Publicado en Aging (Albany NY) (2020)

Characterization of whole-genome autosomal differences of DNA methylation between men and women

por Singmann, Paula, Shem-Tov, Doron, Wahl, Simone, Grallert, Harald, Fiorito, Giovanni, Shin, So-Youn, Schramm, Katharina, Wolf, Petra, Kunze, Sonja, Baran, Yael, Guarrera, Simonetta, Vineis, Paolo, Krogh, Vittorio, Panico, Salvatore, Tumino, Rosario, Kretschmer, Anja, Gieger, Christian, Peters, Annette, Prokisch, Holger, Relton, Caroline L., Matullo, Giuseppe, Illig, Thomas, Waldenberger, Melanie, Halperin, Eran
Publicado en Epigenetics Chromatin (2015)

Metastable DNA methylation sites associated with longitudinal lung function decline and aging in humans: an epigenome-wide study in the NAS and KORA cohorts

por Carmona, Juan Jose, Barfield, Richard T., Panni, Tommaso, Nwanaji-Enwerem, Jamaji C., Just, Allan C., Hutchinson, John N., Colicino, Elena, Karrasch, Stefan, Wahl, Simone, Kunze, Sonja, Jafari, Nadereh, Zheng, Yinan, Hou, Lifang, DeMeo, Dawn L., Litonjua, Augusto A., Vokonas, Pantel S., Peters, Annette, Lin, Xihong, Schwartz, Joel, Schulz, Holger, Baccarelli, Andrea A.
Publicado en Epigenetics (2018)

DNA Methylation of Lipid-Related Genes Affects Blood Lipid Levels

por Pfeiffer, Liliane, Wahl, Simone, Pilling, Luke C., Reischl, Eva, Sandling, Johanna K., Kunze, Sonja, Holdt, Lesca M., Kretschmer, Anja, Schramm, Katharina, Adamski, Jerzy, Klopp, Norman, Illig, Thomas, Hedman, Åsa K., Roden, Michael, Hernandez, Dena G., Singleton, Andrew B., Thasler, Wolfgang E., Grallert, Harald, Gieger, Christian, Herder, Christian, Teupser, Daniel, Meisinger, Christa, Spector, Timothy D., Kronenberg, Florian, Prokisch, Holger, Melzer, David, Peters, Annette, Deloukas, Panos, Ferrucci, Luigi, Waldenberger, Melanie
Publicado en Circ Cardiovasc Genet (2015)

Epigenetic upregulation of FKBP5 by aging and stress contributes to NF-κB–driven inflammation and cardiovascular risk

por Zannas, Anthony S., Jia, Meiwen, Hafner, Kathrin, Baumert, Jens, Wiechmann, Tobias, Pape, Julius C., Arloth, Janine, Ködel, Maik, Martinelli, Silvia, Roitman, Maria, Röh, Simone, Haehle, Andreas, Emeny, Rebecca T., Iurato, Stella, Carrillo-Roa, Tania, Lahti, Jari, Räikkönen, Katri, Eriksson, Johan G., Drake, Amanda J., Waldenberger, Melanie, Wahl, Simone, Kunze, Sonja, Lucae, Susanne, Bradley, Bekh, Gieger, Christian, Hausch, Felix, Smith, Alicia K., Ressler, Kerry J., Müller-Myhsok, Bertram, Ladwig, Karl-Heinz, Rein, Theo, Gassen, Nils C., Binder, Elisabeth B.
Publicado en Proc Natl Acad Sci U S A (2019)

Validated inference of smoking habits from blood with a finite DNA methylation marker set

por Maas, Silvana C. E., Vidaki, Athina, Wilson, Rory, Teumer, Alexander, Liu, Fan, van Meurs, Joyce B. J., Uitterlinden, André G., Boomsma, Dorret I., de Geus, Eco J. C., Willemsen, Gonneke, van Dongen, Jenny, van der Kallen, Carla J. H., Slagboom, P. Eline, Beekman, Marian, van Heemst, Diana, van den Berg, Leonard H., Duijts, Liesbeth, Jaddoe, Vincent W. V., Ladwig, Karl-Heinz, Kunze, Sonja, Peters, Annette, Ikram, M. Arfan, Grabe, Hans J., Felix, Janine F., Waldenberger, Melanie, Franco, Oscar H., Ghanbari, Mohsen, Kayser, Manfred
Publicado en Eur J Epidemiol (2019)

DNAm-based signatures of accelerated aging and mortality in blood are associated with low renal function

por Matías-García, Pamela R., Ward-Caviness, Cavin K., Raffield, Laura M., Gao, Xu, Zhang, Yan, Wilson, Rory, Gào, Xīn, Nano, Jana, Bostom, Andrew, Colicino, Elena, Correa, Adolfo, Coull, Brent, Eaton, Charles, Hou, Lifang, Just, Allan C., Kunze, Sonja, Lange, Leslie, Lange, Ethan, Lin, Xihong, Liu, Simin, Nwanaji-Enwerem, Jamaji C., Reiner, Alex, Shen, Jincheng, Schöttker, Ben, Vokonas, Pantel, Zheng, Yinan, Young, Bessie, Schwartz, Joel, Horvath, Steve, Lu, Ake, Whitsel, Eric A., Koenig, Wolfgang, Adamski, Jerzy, Winkelmann, Juliane, Brenner, Hermann, Baccarelli, Andrea A., Gieger, Christian, Peters, Annette, Franceschini, Nora, Waldenberger, Melanie
Publicado en Clin Epigenetics (2021)

Genetically defined elevated homocysteine levels do not result in widespread changes of DNA methylation in leukocytes

por Mandaviya, Pooja R., Joehanes, Roby, Aïssi, Dylan, Kühnel, Brigitte, Marioni, Riccardo E., Truong, Vinh, Stolk, Lisette, Beekman, Marian, Bonder, Marc Jan, Franke, Lude, Gieger, Christian, Huan, Tianxiao, Ikram, M. Arfan, Kunze, Sonja, Liang, Liming, Lindemans, Jan, Liu, Chunyu, McRae, Allan F., Mendelson, Michael M., Müller-Nurasyid, Martina, Peters, Annette, Slagboom, P. Eline, Starr, John M., Trégouët, David-Alexandre, Uitterlinden, André G., van Greevenbroek, Marleen M. J., van Heemst, Diana, van Iterson, Maarten, Wells, Philip S., Yao, Chen, Deary, Ian J., Gagnon, France, Heijmans, Bastiaan T., Levy, Daniel, Morange, Pierre-Emmanuel, Waldenberger, Melanie, Heil, Sandra G., van Meurs, Joyce B. J.
Publicado en PLoS One (2017)

Association of Methylation Signals With Incident Coronary Heart Disease in an Epigenome-Wide Assessment of Circulating Tumor Necrosis Factor α

por Aslibekyan, Stella, Agha, Golareh, Colicino, Elena, Do, Anh N., Lahti, Jari, Ligthart, Symen, Marioni, Riccardo E., Marzi, Carola, Mendelson, Michael M., Tanaka, Toshiko, Wielscher, Matthias, Absher, Devin M., Ferrucci, Luigi, Franco, Oscar H., Gieger, Christian, Grallert, Harald, Hernandez, Dena, Huan, Tianxiao, Iurato, Stella, Joehanes, Roby, Just, Allan C., Kunze, Sonja, Lin, Honghuang, Liu, Chunyu, Meigs, James B., van Meurs, Joyce B. J., Moore, Ann Zenobia, Peters, Annette, Prokisch, Holger, Räikkönen, Katri, Rathmann, Wolfgang, Roden, Michael, Schramm, Katharina, Schwartz, Joel D., Starr, John M., Uitterlinden, André G., Vokonas, Pantel, Waldenberger, Melanie, Yao, Chen, Zhi, Degui, Baccarelli, Andrea A., Bandinelli, Stefania, Deary, Ian J., Dehghan, Abbas, Eriksson, Johan, Herder, Christian, Jarvelin, Marjo-Riitta, Levy, Daniel, Arnett, Donna K.
Publicado en JAMA Cardiol (2018)