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Anxiety Associated Increased CpG Methylation in the Promoter of Asb1: A Translational Approach Evidenced by Epidemiological and Clinical Studies and a Murine Model

Epigenetic regulation in anxiety is suggested, but evidence from large studies is needed. We conducted an epigenome-wide association study (EWAS) on anxiety in a population-based cohort and validated our finding in a clinical cohort as well as a murine model. In the KORA cohort, participants (n=1522...

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Opis bibliograficzny
Wydane w:Neuropsychopharmacology
Główni autorzy: Emeny, Rebecca T, Baumert, Jens, Zannas, Anthony S, Kunze, Sonja, Wahl, Simone, Iurato, Stella, Arloth, Janine, Erhardt, Angelika, Balsevich, Georgia, Schmidt, Mathias V, Weber, Peter, Kretschmer, Anja, Pfeiffer, Liliane, Kruse, Johannes, Strauch, Konstantin, Roden, Michael, Herder, Christian, Koenig, Wolfgang, Gieger, Christian, Waldenberger, Melanie, Peters, Annette, Binder, Elisabeth B, Ladwig, Karl-Heinz
Format: Artigo
Język:Inglês
Wydane: Nature Publishing Group 2018
Hasła przedmiotowe:
Dostęp online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5729551/
https://ncbi.nlm.nih.gov/pubmed/28540928
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npp.2017.102
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