RL-SKAT: An Exact and Efficient Score Test for Heritability and Set Tests

Testing for the existence of variance components in linear mixed models is a fundamental task in many applicative fields. In statistical genetics, the score test has recently become instrumental in the task of testing an association between a set of genetic markers and a phenotype. With few markers,...

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Detalhes bibliográficos
Publicado no:Genetics
Main Authors: Schweiger, Regev, Weissbrod, Omer, Rahmani, Elior, Müller-Nurasyid, Martina, Kunze, Sonja, Gieger, Christian, Waldenberger, Melanie, Rosset, Saharon, Halperin, Eran
Formato: Artigo
Idioma:Inglês
Publicado em: Genetics Society of America 2017
Assuntos:
Investigations
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5714447/
https://ncbi.nlm.nih.gov/pubmed/29025915
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.117.300395
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